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In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata excitatory and inhibitory axon sprouting, and increased staining for N-methyl-D-aspartate, AMPA and GABA(A) receptors.
Mathern GW, Bertram EH 3rd, Babb TL, Pretorius JK, Kuhlman PA, Spradlin S, Mendoza D. Mathern GW, et al. Among authors: pretorius jk. Neuroscience. 1997 Apr;77(4):1003-19. doi: 10.1016/s0306-4522(96)00516-7. Neuroscience. 1997. PMID: 9130782
Human hippocampal AMPA and NMDA mRNA levels in temporal lobe epilepsy patients.
Mathern GW, Pretorius JK, Kornblum HI, Mendoza D, Lozada A, Leite JP, Chimelli LM, Fried I, Sakamoto AC, Assirati JA, Lévesque MF, Adelson PD, Peacock WJ. Mathern GW, et al. Among authors: pretorius jk. Brain. 1997 Nov;120 ( Pt 11):1937-59. doi: 10.1093/brain/120.11.1937. Brain. 1997. PMID: 9397013
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