Ura M - Search Results

1

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue.

Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, Shimma N, Umeda I, Ishitsuka H. Miwa M, et al. Among authors: ura m. Eur J Cancer. 1998 Jul;34(8):1274-81. doi: 10.1016/s0959-8049(98)00058-6. Eur J Cancer. 1998. PMID: 9849491

2

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

Hattori K, Kohchi Y, Oikawa N, Suda H, Ura M, Ishikawa T, Miwa M, Endoh M, Eda H, Tanimura H, Kawashima A, Horii I, Ishitsuka H, Shimma N. Hattori K, et al. Among authors: ura m. Bioorg Med Chem Lett. 2003 Mar 10;13(5):867-72. doi: 10.1016/s0960-894x(02)01082-x. Bioorg Med Chem Lett. 2003. PMID: 12617910

3

Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889.

Endo M, Miwa M, Eda H, Ura M, Tanimura H, Ishikawa T, Miyazaki-Nose T, Hattori K, Shimma N, Yamada-Okabe H, Ishitsuka H. Endo M, et al. Among authors: ura m. Int J Cancer. 2003 Sep 20;106(5):799-805. doi: 10.1002/ijc.11276. Int J Cancer. 2003. PMID: 12866042

4

The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase.

Eda H, Ura M, F-Ouchi K, Tanaka Y, Miwa M, Ishitsuka H. Eda H, et al. Among authors: ura m. Cancer Res. 1998 Mar 15;58(6):1165-9. Cancer Res. 1998. PMID: 9515801

5

High susceptibility of human cancer xenografts with higher levels of cytidine deaminase to a 2'-deoxycytidine antimetabolite, 2'-deoxy-2'-methylidenecytidine.

Miwa M, Eda H, Ura M, Ouchi KF, Keith DD, Foley LH, Ishitsuka H. Miwa M, et al. Among authors: ura m. Clin Cancer Res. 1998 Feb;4(2):493-7. Clin Cancer Res. 1998. PMID: 9516941

6

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, capecitabine.

Shimma N, Umeda I, Arasaki M, Murasaki C, Masubuchi K, Kohchi Y, Miwa M, Ura M, Sawada N, Tahara H, Kuruma I, Horii I, Ishitsuka H. Shimma N, et al. Among authors: ura m. Bioorg Med Chem. 2000 Jul;8(7):1697-706. doi: 10.1016/s0968-0896(00)00087-0. Bioorg Med Chem. 2000. PMID: 10976516

7

Investigation of 5-FU disposition after oral administration of capecitabine, a triple-prodrug of 5-FU, using a physiologically based pharmacokinetic model in a human cancer xenograft model: comparison of the simulated 5-FU exposures in the tumour tissue between human and xenograft model.

Tsukamoto Y, Kato Y, Ura M, Horii I, Ishikawa T, Ishitsuka H, Sugiyama Y. Tsukamoto Y, et al. Among authors: ura m. Biopharm Drug Dispos. 2001 Jan;22(1):1-14. doi: 10.1002/bdd.250. Biopharm Drug Dispos. 2001. PMID: 11745902

8

Selective inhibition of spontaneous pulmonary metastasis of Lewis lung carcinoma by 5'-deoxy-5-fluorouridine.

Ishikawa T, Ura M, Yamamoto T, Tanaka Y, Ishitsuka H. Ishikawa T, et al. Among authors: ura m. Int J Cancer. 1995 May 16;61(4):516-21. doi: 10.1002/ijc.2910610415. Int J Cancer. 1995. PMID: 7759157

9

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine.

Eda H, Fujimoto K, Watanabe S, Ura M, Hino A, Tanaka Y, Wada K, Ishitsuka H. Eda H, et al. Among authors: ura m. Cancer Chemother Pharmacol. 1993;32(5):333-8. doi: 10.1007/BF00735915. Cancer Chemother Pharmacol. 1993. PMID: 8339382

10

A physiologically based pharmacokinetic analysis of capecitabine, a triple prodrug of 5-FU, in humans: the mechanism for tumor-selective accumulation of 5-FU.

Tsukamoto Y, Kato Y, Ura M, Horii I, Ishitsuka H, Kusuhara H, Sugiyama Y. Tsukamoto Y, et al. Among authors: ura m. Pharm Res. 2001 Aug;18(8):1190-202. doi: 10.1023/a:1010939329562. Pharm Res. 2001. PMID: 11587492

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

130 results

Search Page

Filters