Rowley M - Search Results

1

Substituted pyrazoles as novel selective ligands for the human dopamine D4 receptor.

Bourrain S, Collins I, Neduvelil JG, Rowley M, Leeson PD, Patel S, Patel S, Emms F, Marwood R, Chapman KL, Fletcher AE, Showell GA. Bourrain S, et al. Among authors: rowley m. Bioorg Med Chem. 1998 Oct;6(10):1731-43. doi: 10.1016/s0968-0896(98)00134-5. Bioorg Med Chem. 1998. PMID: 9839003

2

5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors.

Rowley M, Broughton HB, Collins I, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Leeson PD. Rowley M, et al. J Med Chem. 1996 May 10;39(10):1943-5. doi: 10.1021/jm960072u. J Med Chem. 1996. PMID: 8642551 No abstract available.

3

4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor.

Rowley M, Collins I, Broughton HB, Davey WB, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Ball R, Leeson PD. Rowley M, et al. J Med Chem. 1997 Jul 18;40(15):2374-85. doi: 10.1021/jm970111h. J Med Chem. 1997. PMID: 9240352

4

3-(1-piperazinyl)-4,5-dihydro-1H-benzo[g]indazoles: high affinity ligands for the human dopamine D4 receptor with improved selectivity over ion channels.

Collins I, Rowley M, Davey WB, Emms F, Marwood R, Patel S, Patel S, Fletcher A, Ragan IC, Leeson PD, Scott AL, Broten T. Collins I, et al. Among authors: rowley m. Bioorg Med Chem. 1998 Jun;6(6):743-53. doi: 10.1016/s0968-0896(98)00028-5. Bioorg Med Chem. 1998. PMID: 9681140

5

4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors.

Moore KW, Bonner K, Jones EA, Emms F, Leeson PD, Marwood R, Patel S, Patel S, Rowley M, Thomas S, Carling RW. Moore KW, et al. Among authors: rowley m. Bioorg Med Chem Lett. 1999 May 3;9(9):1285-90. doi: 10.1016/s0960-894x(99)00169-9. Bioorg Med Chem Lett. 1999. PMID: 10340615

6

3-(4-Piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT2A antagonists.

Crawforth J, Goodacre S, Maxey R, Bourrain S, Patel S, Marwood R, O'Connor D, Herbert R, Hutson P, Rowley M. Crawforth J, et al. Among authors: rowley m. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2701-3. doi: 10.1016/s0960-894x(00)00559-x. Bioorg Med Chem Lett. 2000. PMID: 11133072

7

3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT(2A) receptor antagonists.

Rowley M, Hallett DJ, Goodacre S, Moyes C, Crawforth J, Sparey TJ, Patel S, Marwood R, Patel S, Thomas S, Hitzel L, O'Connor D, Szeto N, Castro JL, Hutson PH, MacLeod AM. Rowley M, et al. J Med Chem. 2001 May 10;44(10):1603-14. doi: 10.1021/jm0004998. J Med Chem. 2001. PMID: 11334570

8

3-Heteroaryl-2-pyridones: benzodiazepine site ligands with functional delectivity for alpha 2/alpha 3-subtypes of human GABA(A) receptor-ion channels.

Collins I, Moyes C, Davey WB, Rowley M, Bromidge FA, Quirk K, Atack JR, McKernan RM, Thompson SA, Wafford K, Dawson GR, Pike A, Sohal B, Tsou NN, Ball RG, Castro JL. Collins I, et al. Among authors: rowley m. J Med Chem. 2002 Apr 25;45(9):1887-900. doi: 10.1021/jm0110789. J Med Chem. 2002. PMID: 11960500

9

3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally active antagonists of the glycine site on the NMDA receptor.

Kulagowski JJ, Baker R, Curtis NR, Leeson PD, Mawer IM, Moseley AM, Ridgill MP, Rowley M, Stansfield I, Foster AC, et al. Kulagowski JJ, et al. Among authors: rowley m. J Med Chem. 1994 May 13;37(10):1402-5. doi: 10.1021/jm00036a002. J Med Chem. 1994. PMID: 8182696 No abstract available.

10

3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting by antagonism at the glycine site of the N-methyl-D-aspartate receptor complex.

Rowley M, Leeson PD, Stevenson GI, Moseley AM, Stansfield I, Sanderson I, Robinson L, Baker R, Kemp JA, Marshall GR, et al. Rowley M, et al. J Med Chem. 1993 Oct 29;36(22):3386-96. doi: 10.1021/jm00074a020. J Med Chem. 1993. PMID: 8230129

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