McKechnie K - Search Results

1

Dual D2-receptor and beta2-adrenoceptor agonists for the treatment of airway diseases. 1. Discovery and biological evaluation of some 7-(2-aminoethyl)-4-hydroxybenzothiazol-2(3H)-one analogues.

Bonnert RV, Brown RC, Chapman D, Cheshire DR, Dixon J, Ince F, Kinchin EC, Lyons AJ, Davis AM, Hallam C, Harper ST, Unitt JF, Dougall IG, Jackson DM, McKechnie K, Young A, Simpson WT. Bonnert RV, et al. Among authors: mckechnie k. J Med Chem. 1998 Dec 3;41(25):4915-7. doi: 10.1021/jm980421f. J Med Chem. 1998. PMID: 9836607 No abstract available.

2

From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y₂ receptor.

Kindon N, Davis A, Dougall I, Dixon J, Johnson T, Walters I, Thom S, McKechnie K, Meghani P, Stocks MJ. Kindon N, et al. Among authors: mckechnie k. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4849-4853. doi: 10.1016/j.bmcl.2017.09.043. Epub 2017 Sep 21. Bioorg Med Chem Lett. 2017. PMID: 28958619

3

Pharmacological studies on prostanoid receptors in the rabbit isolated saphenous vein: a comparison with the rabbit isolated ear artery.

Lydford SJ, McKechnie KC, Dougall IG. Lydford SJ, et al. Among authors: mckechnie kc. Br J Pharmacol. 1996 Jan;117(1):13-20. doi: 10.1111/j.1476-5381.1996.tb15148.x. Br J Pharmacol. 1996. PMID: 8825337 Free PMC article.

4

Agonist-antagonist interactions at angiotensin receptors: application of a two-state receptor model.

Robertson MJ, Dougall IG, Harper D, McKechnie KC, Leff P. Robertson MJ, et al. Among authors: mckechnie kc. Trends Pharmacol Sci. 1994 Oct;15(10):364-9. doi: 10.1016/0165-6147(94)90156-2. Trends Pharmacol Sci. 1994. PMID: 7809951 Review.

5

A three-state receptor model of agonist action.

Leff P, Scaramellini C, Law C, McKechnie K. Leff P, et al. Among authors: mckechnie k. Trends Pharmacol Sci. 1997 Oct;18(10):355-62. doi: 10.1016/s0165-6147(97)01105-x. Trends Pharmacol Sci. 1997. PMID: 9357320 Review.

6

Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein.

Lydford SJ, McKechnie KC, Leff P. Lydford SJ, et al. Among authors: mckechnie kc. Prostaglandins. 1996 Aug;52(2):125-39. doi: 10.1016/0090-6980(96)00058-5. Prostaglandins. 1996. PMID: 8880898

7

Quantitative analysis of the agonist and antagonist actions of some ATP analogues at P2X-purinoceptors in the rabbit ear artery.

Leff P, Wood BE, O'Connor SE, McKechnie K. Leff P, et al. Among authors: mckechnie k. Br J Pharmacol. 1993 Feb;108(2):490-6. doi: 10.1111/j.1476-5381.1993.tb12830.x. Br J Pharmacol. 1993. PMID: 8448598 Free PMC article.

8

Pharmacological analysis of ecto-ATPase inhibition: evidence for combined enzyme inhibition and receptor antagonism in P2X-purinoceptor ligands.

Crack BE, Beukers MW, McKechnie KC, Ijzerman AP, Leff P. Crack BE, et al. Among authors: mckechnie kc. Br J Pharmacol. 1994 Dec;113(4):1432-8. doi: 10.1111/j.1476-5381.1994.tb17157.x. Br J Pharmacol. 1994. PMID: 7889301 Free PMC article.

9

Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase.

Crack BE, Pollard CE, Beukers MW, Roberts SM, Hunt SF, Ingall AH, McKechnie KC, IJzerman AP, Leff P. Crack BE, et al. Among authors: mckechnie kc. Br J Pharmacol. 1995 Jan;114(2):475-81. doi: 10.1111/j.1476-5381.1995.tb13251.x. Br J Pharmacol. 1995. PMID: 7533620 Free PMC article.

10

Characterization of the prostaglandin E2 sensitive (EP)-receptor in the rat isolated trachea.

Lydford SJ, McKechnie K. Lydford SJ, et al. Among authors: mckechnie k. Br J Pharmacol. 1994 May;112(1):133-6. doi: 10.1111/j.1476-5381.1994.tb13042.x. Br J Pharmacol. 1994. PMID: 8032634 Free PMC article.

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