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Glutathione transferase P1-1: self-preservation of an anti-cancer enzyme.
Ricci G, Caccuri AM, Lo Bello M, Parker MW, Nuccetelli M, Turella P, Stella L, Di Iorio EE, Federici G. Ricci G, et al. Among authors: lo bello m. Biochem J. 2003 Nov 15;376(Pt 1):71-6. doi: 10.1042/BJ20030860. Biochem J. 2003. PMID: 12877654 Free PMC article.
Site-directed mutagenesis of human glutathione transferase P1-1. Spectral, kinetic, and structural properties of Cys-47 and Lys-54 mutants.
Lo Bello M, Battistoni A, Mazzetti AP, Board PG, Muramatsu M, Federici G, Ricci G. Lo Bello M, et al. J Biol Chem. 1995 Jan 20;270(3):1249-53. J Biol Chem. 1995. PMID: 7836387 Free article.
The induced cooperativity toward glutathione, as a consequence of mutation of Lys-54 to alanine, clearly parallels that observed for the Cys-47 mutant enzymes (see the preceding paper (Ricci, G., Lo Bello, M., Caccuri, A. M., Pastore, A., Nuccetelli, …
The induced cooperativity toward glutathione, as a consequence of mutation of Lys-54 to alanine, clearly parallels that observed for the Cys …
82 results