Groudine M - Search Results

1

The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus.

Epner E, Reik A, Cimbora D, Telling A, Bender MA, Fiering S, Enver T, Martin DI, Kennedy M, Keller G, Groudine M. Epner E, et al. Among authors: groudine m. Mol Cell. 1998 Oct;2(4):447-55. doi: 10.1016/s1097-2765(00)80144-6. Mol Cell. 1998. PMID: 9809066 Free article.

2

A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus.

Bulger M, Schübeler D, Bender MA, Hamilton J, Farrell CM, Hardison RC, Groudine M. Bulger M, et al. Among authors: groudine m. Mol Cell Biol. 2003 Aug;23(15):5234-44. doi: 10.1128/MCB.23.15.5234-5244.2003. Mol Cell Biol. 2003. PMID: 12861010 Free PMC article.

3

Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription.

Bender MA, Byron R, Ragoczy T, Telling A, Bulger M, Groudine M. Bender MA, et al. Among authors: groudine m. Blood. 2006 Aug 15;108(4):1395-401. doi: 10.1182/blood-2006-04-014431. Epub 2006 Apr 27. Blood. 2006. PMID: 16645164 Free PMC article.

4

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

Sawado T, Halow J, Bender MA, Groudine M. Sawado T, et al. Among authors: groudine m. Genes Dev. 2003 Apr 15;17(8):1009-18. doi: 10.1101/gad.1072303. Epub 2003 Apr 2. Genes Dev. 2003. PMID: 12672691 Free PMC article.

5

Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region.

Kim CG, Epner EM, Forrester WC, Groudine M. Kim CG, et al. Among authors: groudine m. Genes Dev. 1992 Jun;6(6):928-38. doi: 10.1101/gad.6.6.928. Genes Dev. 1992. PMID: 1592262 Free article.

6

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

Forrester WC, Epner E, Driscoll MC, Enver T, Brice M, Papayannopoulou T, Groudine M. Forrester WC, et al. Among authors: groudine m. Genes Dev. 1990 Oct;4(10):1637-49. doi: 10.1101/gad.4.10.1637. Genes Dev. 1990. PMID: 2249769 Free article.

7

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M. Fiering S, et al. Among authors: groudine m. Genes Dev. 1995 Sep 15;9(18):2203-13. doi: 10.1101/gad.9.18.2203. Genes Dev. 1995. PMID: 7557375 Free article.

8

An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the beta-globin locus control region.

Fiering S, Kim CG, Epner EM, Groudine M. Fiering S, et al. Among authors: groudine m. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8469-73. doi: 10.1073/pnas.90.18.8469. Proc Natl Acad Sci U S A. 1993. PMID: 8378321 Free PMC article.

9

Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

Hug BA, Wesselschmidt RL, Fiering S, Bender MA, Epner E, Groudine M, Ley TJ. Hug BA, et al. Among authors: groudine m. Mol Cell Biol. 1996 Jun;16(6):2906-12. doi: 10.1128/MCB.16.6.2906. Mol Cell Biol. 1996. PMID: 8649401 Free PMC article.

10

Regulation of beta-globin gene expression: straightening out the locus.

Martin DI, Fiering S, Groudine M. Martin DI, et al. Among authors: groudine m. Curr Opin Genet Dev. 1996 Aug;6(4):488-95. doi: 10.1016/s0959-437x(96)80072-4. Curr Opin Genet Dev. 1996. PMID: 8791532 Review.

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