Roberts RJ - Search Results

1

Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.

O'Gara M, Horton JR, Roberts RJ, Cheng X. O'Gara M, et al. Among authors: roberts rj. Nat Struct Biol. 1998 Oct;5(10):872-7. doi: 10.1038/2312. Nat Struct Biol. 1998. PMID: 9783745

2

Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.

O'Gara M, Klimasauskas S, Roberts RJ, Cheng X. O'Gara M, et al. Among authors: roberts rj. J Mol Biol. 1996 Sep 6;261(5):634-45. doi: 10.1006/jmbi.1996.0489. J Mol Biol. 1996. PMID: 8800212

3

A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase.

O'Gara M, Roberts RJ, Cheng X. O'Gara M, et al. Among authors: roberts rj. J Mol Biol. 1996 Nov 8;263(4):597-606. doi: 10.1006/jmbi.1996.0601. J Mol Biol. 1996. PMID: 8918941

4

DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.

Kumar S, Horton JR, Jones GD, Walker RT, Roberts RJ, Cheng X. Kumar S, et al. Among authors: roberts rj. Nucleic Acids Res. 1997 Jul 15;25(14):2773-83. doi: 10.1093/nar/25.14.2773. Nucleic Acids Res. 1997. PMID: 9207024 Free PMC article.

5

Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide.

O'Gara M, Zhang X, Roberts RJ, Cheng X. O'Gara M, et al. Among authors: roberts rj. J Mol Biol. 1999 Mar 26;287(2):201-9. doi: 10.1006/jmbi.1999.2608. J Mol Biol. 1999. PMID: 10080885

6

Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 Å.

Horton JR, Yang J, Zhang X, Petronzio T, Fomenkov A, Wilson GG, Roberts RJ, Cheng X. Horton JR, et al. Among authors: roberts rj. Nucleic Acids Res. 2020 Feb 20;48(3):1466-1478. doi: 10.1093/nar/gkz1195. Nucleic Acids Res. 2020. PMID: 31879785 Free PMC article.

7

HhaI methyltransferase flips its target base out of the DNA helix.

Klimasauskas S, Kumar S, Roberts RJ, Cheng X. Klimasauskas S, et al. Among authors: roberts rj. Cell. 1994 Jan 28;76(2):357-69. doi: 10.1016/0092-8674(94)90342-5. Cell. 1994. PMID: 8293469

8

Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.

Cheng X, Kumar S, Posfai J, Pflugrath JW, Roberts RJ. Cheng X, et al. Among authors: roberts rj. Cell. 1993 Jul 30;74(2):299-307. doi: 10.1016/0092-8674(93)90421-l. Cell. 1993. PMID: 8343957

9

Base flipping.

Roberts RJ, Cheng X. Roberts RJ, et al. Annu Rev Biochem. 1998;67:181-98. doi: 10.1146/annurev.biochem.67.1.181. Annu Rev Biochem. 1998. PMID: 9759487 Review.

10

Crystal structure of the HhaI DNA methyltransferase.

Cheng X, Kumar S, Klimasauskas S, Roberts RJ. Cheng X, et al. Among authors: roberts rj. Cold Spring Harb Symp Quant Biol. 1993;58:331-8. doi: 10.1101/sqb.1993.058.01.039. Cold Spring Harb Symp Quant Biol. 1993. PMID: 7956046 No abstract available.

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