Stirling D - Search Results

1

CC-3052: a water-soluble analog of thalidomide and potent inhibitor of activation-induced TNF-alpha production.

Marriott JB, Westby M, Cookson S, Guckian M, Goodbourn S, Muller G, Shire MG, Stirling D, Dalgleish AG. Marriott JB, et al. Among authors: stirling d. J Immunol. 1998 Oct 15;161(8):4236-43. J Immunol. 1998. PMID: 9780198

2

Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity.

Dredge K, Marriott JB, Todryk SM, Muller GW, Chen R, Stirling DI, Dalgleish AG. Dredge K, et al. J Immunol. 2002 May 15;168(10):4914-9. doi: 10.4049/jimmunol.168.10.4914. J Immunol. 2002. PMID: 11994441

3

Immunotherapeutic and antitumour potential of thalidomide analogues.

Marriott JB, Muller G, Stirling D, Dalgleish AG. Marriott JB, et al. Among authors: stirling d. Expert Opin Biol Ther. 2001 Jul;1(4):675-82. doi: 10.1517/14712598.1.4.675. Expert Opin Biol Ther. 2001. PMID: 11727503 Review.

4

Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells.

Marriott JB, Clarke IA, Dredge K, Muller G, Stirling D, Dalgleish AG. Marriott JB, et al. Among authors: stirling d. Clin Exp Immunol. 2002 Oct;130(1):75-84. doi: 10.1046/j.1365-2249.2002.01954.x. Clin Exp Immunol. 2002. PMID: 12296856 Free PMC article. Clinical Trial.

5

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects.

Dredge K, Marriott JB, Macdonald CD, Man HW, Chen R, Muller GW, Stirling D, Dalgleish AG. Dredge K, et al. Among authors: stirling d. Br J Cancer. 2002 Nov 4;87(10):1166-72. doi: 10.1038/sj.bjc.6600607. Br J Cancer. 2002. PMID: 12402158 Free PMC article.

6

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins.

Marriott JB, Clarke IA, Czajka A, Dredge K, Childs K, Man HW, Schafer P, Govinda S, Muller GW, Stirling DI, Dalgleish AG. Marriott JB, et al. Cancer Res. 2003 Feb 1;63(3):593-9. Cancer Res. 2003. PMID: 12566301

7

Thalidomide analogs and PDE4 inhibition.

Muller GW, Shire MG, Wong LM, Corral LG, Patterson RT, Chen Y, Stirling DI. Muller GW, et al. Among authors: stirling di. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2669-74. doi: 10.1016/s0960-894x(98)00475-2. Bioorg Med Chem Lett. 1998. PMID: 9873600

8

Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha.

Corral LG, Haslett PA, Muller GW, Chen R, Wong LM, Ocampo CJ, Patterson RT, Stirling DI, Kaplan G. Corral LG, et al. Among authors: stirling di. J Immunol. 1999 Jul 1;163(1):380-6. J Immunol. 1999. PMID: 10384139

9

Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers.

Bartlett JB, Michael A, Clarke IA, Dredge K, Nicholson S, Kristeleit H, Polychronis A, Pandha H, Muller GW, Stirling DI, Zeldis J, Dalgleish AG. Bartlett JB, et al. Among authors: stirling di. Br J Cancer. 2004 Mar 8;90(5):955-61. doi: 10.1038/sj.bjc.6601579. Br J Cancer. 2004. PMID: 14997189 Free PMC article. Clinical Trial.

10

Use of IMiD3, a thalidomide analog, as an adjunct to therapy for experimental tuberculous meningitis.

Tsenova L, Mangaliso B, Muller G, Chen Y, Freedman VH, Stirling D, Kaplan G. Tsenova L, et al. Among authors: stirling d. Antimicrob Agents Chemother. 2002 Jun;46(6):1887-95. doi: 10.1128/AAC.46.6.1887-1895.2002. Antimicrob Agents Chemother. 2002. PMID: 12019105 Free PMC article.

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