La Colla P - Search Results

1

Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

Artico M, Di Santo R, Costi R, Novellino E, Greco G, Massa S, Tramontano E, Marongiu ME, De Montis A, La Colla P. Artico M, et al. Among authors: la colla p. J Med Chem. 1998 Oct 8;41(21):3948-60. doi: 10.1021/jm9707232. J Med Chem. 1998. PMID: 9767632

2

Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.

Silvestri R, Artico M, De Martino G, Ragno R, Massa S, Loddo R, Murgioni C, Loi AG, La Colla P, Pani A. Silvestri R, et al. Among authors: la colla p. J Med Chem. 2002 Apr 11;45(8):1567-76. doi: 10.1021/jm010904a. J Med Chem. 2002. PMID: 11931611

3

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors.

Di Santo R, Costi R, Artico M, Massa S, Ragno R, Marshall GR, La Colla P. Di Santo R, et al. Among authors: la colla p. Bioorg Med Chem. 2002 Aug;10(8):2511-26. doi: 10.1016/s0968-0896(02)00119-0. Bioorg Med Chem. 2002. PMID: 12057640

4

Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.

Silvestri R, De Martino G, La Regina G, Artico M, Massa S, Vargiu L, Mura M, Loi AG, Marceddu T, La Colla P. Silvestri R, et al. Among authors: la regina g, la colla p. J Med Chem. 2003 Jun 5;46(12):2482-93. doi: 10.1021/jm0211063. J Med Chem. 2003. PMID: 12773052

5

2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays.

Costi R, Santo RD, Artico M, Massa S, Ragno R, Loddo R, La Colla M, Tramontano E, La Colla P, Pani A. Costi R, et al. Among authors: la colla m, la colla p. Bioorg Med Chem. 2004 Jan 2;12(1):199-215. doi: 10.1016/j.bmc.2003.10.005. Bioorg Med Chem. 2004. PMID: 14697785

6

Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.

Ragno R, Mai A, Sbardella G, Artico M, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, La Colla P. Ragno R, et al. Among authors: la colla p. J Med Chem. 2004 Feb 12;47(4):928-34. doi: 10.1021/jm0309856. J Med Chem. 2004. PMID: 14761194

7

6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays.

Costi R, Di Santo R, Artico M, Roux A, Ragno R, Massa S, Tramontano E, La Colla M, Loddo R, Marongiu ME, Pani A, La Colla P. Costi R, et al. Among authors: la colla m, la colla p. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1745-9. doi: 10.1016/j.bmcl.2004.01.037. Bioorg Med Chem Lett. 2004. PMID: 15026063

8

5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.

Mai A, Artico M, Ragno R, Sbardella G, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, Maga G, La Colla P. Mai A, et al. Among authors: la colla p. Bioorg Med Chem. 2005 Mar 15;13(6):2065-77. doi: 10.1016/j.bmc.2005.01.005. Bioorg Med Chem. 2005. PMID: 15727860

9

Synthesis and antimicrobial and cytotoxic activities of pyrrole-containing analogues of trichostatin A.

Massa S, Artico M, Corelli F, Mai A, Di Santo R, Cortes S, Marongiu ME, Pani A, La Colla P. Massa S, et al. Among authors: la colla p. J Med Chem. 1990 Oct;33(10):2845-9. doi: 10.1021/jm00172a026. J Med Chem. 1990. PMID: 2213836

10

Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of isoddA and their phosphates as prodrugs.

Franchetti P, Cappellacci L, Grifantini M, Messini L, abu Sheikha G, Loi AG, Tramontano E, de Montis A, Spiga MG, La Colla P. Franchetti P, et al. Among authors: la colla p. J Med Chem. 1994 Oct 14;37(21):3534-41. doi: 10.1021/jm00047a011. J Med Chem. 1994. PMID: 7523675

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