Okamura H - Search Results

1

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.

Yoshimoto T, Takeda K, Tanaka T, Ohkusu K, Kashiwamura S, Okamura H, Akira S, Nakanishi K. Yoshimoto T, et al. Among authors: okamura h. J Immunol. 1998 Oct 1;161(7):3400-7. J Immunol. 1998. PMID: 9759857

2

LPS-stimulated SJL macrophages produce IL-12 and IL-18 that inhibit IgE production in vitro by induction of IFN-gamma production from CD3intIL-2R beta+ T cells.

Yoshimoto T, Nagai N, Ohkusu K, Ueda H, Okamura H, Nakanishi K. Yoshimoto T, et al. Among authors: okamura h. J Immunol. 1998 Aug 1;161(3):1483-92. J Immunol. 1998. PMID: 9686615

3

IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor.

Hyodo Y, Matsui K, Hayashi N, Tsutsui H, Kashiwamura S, Yamauchi H, Hiroishi K, Takeda K, Tagawa Y, Iwakura Y, Kayagaki N, Kurimoto M, Okamura H, Hada T, Yagita H, Akira S, Nakanishi K, Higashino K. Hyodo Y, et al. Among authors: okamura h. J Immunol. 1999 Feb 1;162(3):1662-8. J Immunol. 1999. PMID: 9973427

4

IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock.

Sakao Y, Takeda K, Tsutsui H, Kaisho T, Nomura F, Okamura H, Nakanishi K, Akira S. Sakao Y, et al. Among authors: okamura h. Int Immunol. 1999 Mar;11(3):471-80. doi: 10.1093/intimm/11.3.471. Int Immunol. 1999. PMID: 10221659

5

Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

Kayagaki N, Yamaguchi N, Nakayama M, Takeda K, Akiba H, Tsutsui H, Okamura H, Nakanishi K, Okumura K, Yagita H. Kayagaki N, et al. Among authors: okamura h. J Immunol. 1999 Aug 15;163(4):1906-13. J Immunol. 1999. PMID: 10438925

6

IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils.

Yoshimoto T, Tsutsui H, Tominaga K, Hoshino K, Okamura H, Akira S, Paul WE, Nakanishi K. Yoshimoto T, et al. Among authors: okamura h. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13962-6. doi: 10.1073/pnas.96.24.13962. Proc Natl Acad Sci U S A. 1999. PMID: 10570181 Free PMC article.

7

IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells.

Tominaga K, Yoshimoto T, Torigoe K, Kurimoto M, Matsui K, Hada T, Okamura H, Nakanishi K. Tominaga K, et al. Among authors: okamura h. Int Immunol. 2000 Feb;12(2):151-60. doi: 10.1093/intimm/12.2.151. Int Immunol. 2000. PMID: 10653850

8

The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit.

Chang JT, Segal BM, Nakanishi K, Okamura H, Shevach EM. Chang JT, et al. Among authors: okamura h. Eur J Immunol. 2000 Apr;30(4):1113-9. doi: 10.1002/(SICI)1521-4141(200004)30:4<1113::AID-IMMU1113>3.0.CO;2-P. Eur J Immunol. 2000. PMID: 10760800 Free article.

9

Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection.

Ohkusu K, Yoshimoto T, Takeda K, Ogura T, Kashiwamura S, Iwakura Y, Akira S, Okamura H, Nakanishi K. Ohkusu K, et al. Among authors: okamura h. Infect Immun. 2000 May;68(5):2449-56. doi: 10.1128/IAI.68.5.2449-2456.2000. Infect Immun. 2000. PMID: 10768930 Free PMC article.

10

IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones.

Tsutsui H, Nakanishi K, Matsui K, Higashino K, Okamura H, Miyazawa Y, Kaneda K. Tsutsui H, et al. Among authors: okamura h. J Immunol. 1996 Nov 1;157(9):3967-73. J Immunol. 1996. PMID: 8892629

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