Perkins C - Search Results

1

"Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.

Fang G, Chang BS, Kim CN, Perkins C, Thompson CB, Bhalla KN. Fang G, et al. Among authors: perkins c. Cancer Res. 1998 Aug 1;58(15):3202-8. Cancer Res. 1998. PMID: 9699642

2

Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells.

Perkins C, Kim CN, Fang G, Bhalla KN. Perkins C, et al. Cancer Res. 1998 Oct 15;58(20):4561-6. Cancer Res. 1998. PMID: 9788601

3

'Loop' domain deletional mutant of Bcl-xL is as effective as p29Bcl-xL in inhibiting radiation-induced cytosolic accumulation of cytochrome c (cyt c), caspase-3 activity, and apoptosis.

Burri SH, Kim CN, Fang G, Chang BS, Perkins C, Harris W, Davis LW, Thompson CB, Bhalla KN. Burri SH, et al. Among authors: perkins c. Int J Radiat Oncol Biol Phys. 1999 Jan 15;43(2):423-30. doi: 10.1016/s0360-3016(98)00385-x. Int J Radiat Oncol Biol Phys. 1999. PMID: 10030271

4

The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.

Perkins CL, Fang G, Kim CN, Bhalla KN. Perkins CL, et al. Cancer Res. 2000 Mar 15;60(6):1645-53. Cancer Res. 2000. PMID: 10749135

Ectopic overexpression of Apaf-1 (2.5-fold) in human acute myelogenous leukemia HL-60 cells (HL-60/Apaf-1 cells) induced apoptosis and sensitized HL-60/Apaf-1 cells to etoposide- and paclitaxel-induced apoptosis (C. Perkins et al., Cancer Res., 58: 4561-4566, 1998). …

Ectopic overexpression of Apaf-1 (2.5-fold) in human acute myelogenous leukemia HL-60 cells (HL-60/Apaf-1 cells) induced apoptosis and sensi …

5

Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels.

Nimmanapalli R, Perkins CL, Orlando M, O'Bryan E, Nguyen D, Bhalla KN. Nimmanapalli R, et al. Among authors: perkins cl. Cancer Res. 2001 Jan 15;61(2):759-63. Cancer Res. 2001. PMID: 11212279

6

Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-x(L).

Perkins C, Kim CN, Fang G, Bhalla KN. Perkins C, et al. Blood. 2000 Feb 1;95(3):1014-22. Blood. 2000. PMID: 10648417 Free article.

7

Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells.

Wen J, Ramadevi N, Nguyen D, Perkins C, Worthington E, Bhalla K. Wen J, et al. Among authors: perkins c. Blood. 2000 Dec 1;96(12):3900-6. Blood. 2000. PMID: 11090076 Free article.

8

Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells.

Nimmanapalli R, Porosnicu M, Nguyen D, Worthington E, O'Bryan E, Perkins C, Bhalla K. Nimmanapalli R, et al. Among authors: perkins c. Clin Cancer Res. 2001 Feb;7(2):350-7. Clin Cancer Res. 2001. PMID: 11234890

9

Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.

Amarante-Mendes GP, Naekyung Kim C, Liu L, Huang Y, Perkins CL, Green DR, Bhalla K. Amarante-Mendes GP, et al. Among authors: perkins cl. Blood. 1998 Mar 1;91(5):1700-5. Blood. 1998. PMID: 9473236 Free article.

10

CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs.

Fang G, Kim CN, Perkins CL, Ramadevi N, Winton E, Wittmann S, Bhalla KN. Fang G, et al. Among authors: perkins cl. Blood. 2000 Sep 15;96(6):2246-53. Blood. 2000. PMID: 10979973 Free article.

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