Benkovic SJ - Search Results

1

A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.

Su Y, Yamashita MM, Greasley SE, Mullen CA, Shim JH, Jennings PA, Benkovic SJ, Wilson IA. Su Y, et al. Among authors: benkovic sj. J Mol Biol. 1998 Aug 21;281(3):485-99. doi: 10.1006/jmbi.1998.1931. J Mol Biol. 1998. PMID: 9698564

2

Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.

Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA. Wolan DW, et al. Among authors: benkovic sj. Biochemistry. 2003 Sep 23;42(37):10904-14. doi: 10.1021/bi030106h. Biochemistry. 2003. PMID: 12974624

3

Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase.

Stura EA, Johnson DL, Inglese J, Smith JM, Benkovic SJ, Wilson IA. Stura EA, et al. Among authors: benkovic sj. J Biol Chem. 1989 Jun 5;264(16):9703-6. J Biol Chem. 1989. PMID: 2656702 Free article.

4

Evaluation of the kinetic mechanism of Escherichia coli glycinamide ribonucleotide transformylase.

Shim JH, Benkovic SJ. Shim JH, et al. Among authors: benkovic sj. Biochemistry. 1998 Jun 16;37(24):8776-82. doi: 10.1021/bi980244k. Biochemistry. 1998. PMID: 9628739

5

Catalytic mechanism of Escherichia coli glycinamide ribonucleotide transformylase probed by site-directed mutagenesis and pH-dependent studies.

Shim JH, Benkovic SJ. Shim JH, et al. Among authors: benkovic sj. Biochemistry. 1999 Aug 3;38(31):10024-31. doi: 10.1021/bi9904609. Biochemistry. 1999. PMID: 10433709

6

New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.

Greasley SE, Yamashita MM, Cai H, Benkovic SJ, Boger DL, Wilson IA. Greasley SE, et al. Among authors: benkovic sj. Biochemistry. 1999 Dec 21;38(51):16783-93. doi: 10.1021/bi991888a. Biochemistry. 1999. PMID: 10606510

7

Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.

Greasley SE, Horton P, Ramcharan J, Beardsley GP, Benkovic SJ, Wilson IA. Greasley SE, et al. Among authors: benkovic sj. Nat Struct Biol. 2001 May;8(5):402-6. doi: 10.1038/87555. Nat Struct Biol. 2001. PMID: 11323713

8

Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase.

Greasley SE, Marsilje TH, Cai H, Baker S, Benkovic SJ, Boger DL, Wilson IA. Greasley SE, et al. Among authors: benkovic sj. Biochemistry. 2001 Nov 13;40(45):13538-47. doi: 10.1021/bi011482+. Biochemistry. 2001. PMID: 11695901

9

Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy.

Chen P, Schulze-Gahmen U, Stura EA, Inglese J, Johnson DL, Marolewski A, Benkovic SJ, Wilson IA. Chen P, et al. Among authors: benkovic sj. J Mol Biol. 1992 Sep 5;227(1):283-92. doi: 10.1016/0022-2836(92)90698-j. J Mol Biol. 1992. PMID: 1522592

10

Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.

Klein C, Chen P, Arevalo JH, Stura EA, Marolewski A, Warren MS, Benkovic SJ, Wilson IA. Klein C, et al. Among authors: benkovic sj. J Mol Biol. 1995 May 26;249(1):153-75. doi: 10.1006/jmbi.1995.0286. J Mol Biol. 1995. PMID: 7776369

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

514 results

Search Page

Filters