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Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains.
Valjakka J, Hemminki A, Niemi S, Söderlund H, Takkinen K, Rouvinen J. Valjakka J, et al. Among authors: hemminki a. J Biol Chem. 2002 Nov 15;277(46):44021-7. doi: 10.1074/jbc.M208392200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196551 Free article.
Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial.
Pakola SA, Clubb JHA, Kudling TV, van der Heijden M, Jirovec E, Arias V, Haybout L, Peltola K, Alanko T, Sormunen J, Pellinen T, Taipale K, Quixabeira DCA, Kistler C, Havunen R, Sorsa S, Santos JM, Cervera-Carrascon V, Hemminki A. Pakola SA, et al. Among authors: hemminki a. J Immunother Cancer. 2025 Jan 27;13(1):e010493. doi: 10.1136/jitc-2024-010493. J Immunother Cancer. 2025. PMID: 39870491 Free PMC article. Clinical Trial.
Durable complete response after combined treatment with tumor-infiltrating lymphocytes and oncolytic adenovirus (TILT-123) in a patient with metastatic mucosal melanoma.
Monberg TJ, Kudling T, Albieri B, Pakola S, Ellebaek E, Donia M, Eefsen RL, von Buchwald C, Kistler C, Santos JM, Clubb J, Haybout L, Westergaard MCW, Quixabeira DCA, Jirovec E, Havunen R, Sorsa S, Cervera-Carrascon V, Hemminki A, Svane IM. Monberg TJ, et al. Among authors: hemminki a. Immunooncol Technol. 2024 Aug 12;24:100726. doi: 10.1016/j.iotech.2024.100726. eCollection 2024 Dec. Immunooncol Technol. 2024. PMID: 39801682 Free PMC article.
Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors.
Jirovec E, Quixabeira DCA, Clubb JHA, Pakola SA, Kudling T, Arias V, Haybout L, Jalkanen K, Alanko T, Monberg T, Khammari A, Dreno B, Svane IM, Block MS, Adamo DA, Mäenpää J, Kistler C, Sorsa S, Hemminki O, Kanerva A, Santos JM, Cervera-Carrascon V, Hemminki A. Jirovec E, et al. Among authors: hemminki a. J Exp Clin Cancer Res. 2024 Nov 6;43(1):297. doi: 10.1186/s13046-024-03219-0. J Exp Clin Cancer Res. 2024. PMID: 39506856 Free PMC article. Clinical Trial.
Survival in Thyroid Cancer in Sweden From 1999 To 2018.
Zitricky F, Koskinen A, Sundquist K, Sundquist J, Liska V, Försti A, Hemminki A, Hemminki K. Zitricky F, et al. Among authors: hemminki a. Clin Epidemiol. 2024 Oct 2;16:659-671. doi: 10.2147/CLEP.S467874. eCollection 2024. Clin Epidemiol. 2024. PMID: 39371051 Free PMC article.
350 results