Pathirana C - Search Results

1

Preparation, resolution, and biological evaluation of 5-aryl-1, 2-dihydro-5H-chromeno[3,4-f]quinolines: potent, orally active, nonsteroidal progesterone receptor agonists.

Edwards JP, Zhi L, Pooley CL, Tegley CM, West SJ, Wang MW, Gottardis MM, Pathirana C, Schrader WT, Jones TK. Edwards JP, et al. Among authors: pathirana c. J Med Chem. 1998 Jul 16;41(15):2779-85. doi: 10.1021/jm980190c. J Med Chem. 1998. PMID: 9667968

2

Discovery of novel intracellular receptor modulating drugs.

Jones TK, Pathirana C, Goldman ME, Hamann LG, Farmer LJ, Ianiro T, Johnson MG, Bender SL, Mais DE, Stein RB. Jones TK, et al. Among authors: pathirana c. J Steroid Biochem Mol Biol. 1996 Jan;56(1-6 Spec No):61-6. doi: 10.1016/0960-0760(95)00224-3. J Steroid Biochem Mol Biol. 1996. PMID: 8603048 Review.

3

Nonsteroidal human progesterone receptor modulators from the marine alga Cymopolia barbata.

Pathirana C, Stein RB, Berger TS, Fenical W, Ianiro T, Mais DE, Torres A, Goldman ME. Pathirana C, et al. Mol Pharmacol. 1995 Mar;47(3):630-5. Mol Pharmacol. 1995. PMID: 7700260

4

Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.

Boehm MF, McClurg MR, Pathirana C, Mangelsdorf D, White SK, Hebert J, Winn D, Goldman ME, Heyman RA. Boehm MF, et al. Among authors: pathirana c. J Med Chem. 1994 Feb 4;37(3):408-14. doi: 10.1021/jm00029a013. J Med Chem. 1994. PMID: 8308867

5

Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate.

Shirley MA, Bennani YL, Boehm MF, Breau AP, Pathirana C, Ulm EH. Shirley MA, et al. Among authors: pathirana c. Drug Metab Dispos. 1996 Mar;24(3):293-302. Drug Metab Dispos. 1996. PMID: 8820419

6

Identification of an activator of the retinoid X receptor.

Pathirana C, Heyman RA, Lazarchik SB. Pathirana C, et al. J Nat Prod. 1994 Oct;57(10):1458-61. doi: 10.1021/np50112a020. J Nat Prod. 1994. PMID: 7807131

7

N-N migration of a carbamoyl group in a pyrazole derivative revealed by NMR.

Pathirana C, Sfouggatakis C, Palaniswamy V. Pathirana C, et al. Magn Reson Chem. 2013 Mar;51(3):184-7. doi: 10.1002/mrc.3921. Epub 2013 Jan 22. Magn Reson Chem. 2013. PMID: 23338988

8

Scalable Asymmetric Synthesis of the All Cis Triamino Cyclohexane Core of BMS-813160.

La Cruz TE, González-Bobes F, Eastgate MD, Sfouggatakis C, Zheng B, Kopp N, Xiao Y, Fan Y, Galindo KA, Pathirana C, Galella MA, Deerberg J. La Cruz TE, et al. Among authors: pathirana c. J Org Chem. 2022 Feb 18;87(4):1996-2011. doi: 10.1021/acs.joc.1c01162. Epub 2021 Aug 6. J Org Chem. 2022. PMID: 34355895

9

Semi-preparative LC-SPE-cryoflow NMR for impurity identifications: use of mother liquor as a better source of impurities.

Rinaldi F, Fan J, Pathirana C, Palaniswamy V. Rinaldi F, et al. Among authors: pathirana c. Magn Reson Chem. 2013 Sep;51(9):517-22. doi: 10.1002/mrc.3979. Epub 2013 Jun 21. Magn Reson Chem. 2013. PMID: 23788325

10

Enantioselective Synthesis of a γ-Secretase Modulator via Vinylogous Dynamic Kinetic Resolution.

Strotman NA, Ramirez A, Simmons EM, Soltani O, Parsons AT, Fan Y, Sawyer JR, Rosner T, Janey JM, Tran K, Li J, La Cruz TE, Pathirana C, Ng AT, Deerberg J. Strotman NA, et al. Among authors: pathirana c. J Org Chem. 2018 Sep 21;83(18):11133-11144. doi: 10.1021/acs.joc.8b01734. Epub 2018 Aug 13. J Org Chem. 2018. PMID: 30102035

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