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Interleukin 6 plays a key role in the development of antigen-induced arthritis.
Ohshima S, Saeki Y, Mima T, Sasai M, Nishioka K, Nomura S, Kopf M, Katada Y, Tanaka T, Suemura M, Kishimoto T. Ohshima S, et al. Among authors: nishioka k. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8222-6. doi: 10.1073/pnas.95.14.8222. Proc Natl Acad Sci U S A. 1998. PMID: 9653168 Free PMC article.
Tumour necrosis factor alpha (TNF-alpha) interferes with Fas-mediated apoptotic cell death on rheumatoid arthritis (RA) synovial cells: a possible mechanism of rheumatoid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RA.
Ohshima S, Mima T, Sasai M, Nishioka K, Shimizu M, Murata N, Yoshikawa H, Nakanishi K, Suemura M, McCloskey RV, Kishimoto T, Saeki Y. Ohshima S, et al. Among authors: nishioka k. Cytokine. 2000 Mar;12(3):281-8. doi: 10.1006/cyto.1999.0552. Cytokine. 2000. PMID: 10704256
Expression of osteopontin at sites of bone erosion in a murine experimental arthritis model of collagen-induced arthritis: possible involvement of osteopontin in bone destruction in arthritis.
Ohshima S, Kobayashi H, Yamaguchi N, Nishioka K, Umeshita-Sasai M, Mima T, Nomura S, Kon S, Inobe M, Uede T, Saeki Y. Ohshima S, et al. Among authors: nishioka k. Arthritis Rheum. 2002 Apr;46(4):1094-101. doi: 10.1002/art.10143. Arthritis Rheum. 2002. PMID: 11953989 Free article.
Enhanced local production of osteopontin in rheumatoid joints.
Ohshima S, Yamaguchi N, Nishioka K, Mima T, Ishii T, Umeshita-Sasai M, Kobayashi H, Shimizu M, Katada Y, Wakitani S, Murata N, Nomura S, Matsuno H, Katayama R, Kon S, Inobe M, Uede T, Kawase I, Saeki Y. Ohshima S, et al. Among authors: nishioka k. J Rheumatol. 2002 Oct;29(10):2061-7. J Rheumatol. 2002. PMID: 12375312
Long-term follow-up of the changes in circulating cytokines, soluble cytokine receptors, and white blood cell subset counts in patients with rheumatoid arthritis (RA) after monoclonal anti-TNF alpha antibody therapy.
Ohshima S, Saeki Y, Mima T, Sasai M, Nishioka K, Ishida H, Shimizu M, Suemura M, McCloskey R, Kishimoto T. Ohshima S, et al. Among authors: nishioka k. J Clin Immunol. 1999 Sep;19(5):305-13. doi: 10.1023/a:1020543625282. J Clin Immunol. 1999. PMID: 10535607 Clinical Trial.
1,945 results