Nitration and inactivation of tyrosine hydroxylase by peroxynitrite.
Blanchard-Fillion B, Souza JM, Friel T, Jiang GC, Vrana K, Sharov V, Barrón L, Schöneich C, Quijano C, Alvarez B, Radi R, Przedborski S, Fernando GS, Horwitz J, Ischiropoulos H.
Blanchard-Fillion B, et al. Among authors: horwitz j.
J Biol Chem. 2001 Dec 7;276(49):46017-23. doi: 10.1074/jbc.M105564200. Epub 2001 Oct 5.
J Biol Chem. 2001.
PMID: 11590168
Free article.
The temporal association of tyrosine nitration with inactivation of TH activity in vitro suggests that this covalent post-translational modification is responsible for the in vivo loss of TH function (Ara, J., Przedborski, S., Naini, A. B., Jackson-Lewis, V., Trifiletti, R …
The temporal association of tyrosine nitration with inactivation of TH activity in vitro suggests that this covalent post-translational modi …