Wang QC - Search Results

1

Aminosyn II effectively blocks renal uptake of 18F-labeled anti-tac disulfide-stabilized Fv.

Carrasquillo JA, Lang L, Whatley M, Herscovitch P, Wang QC, Pastan I, Eckelman WC. Carrasquillo JA, et al. Among authors: wang qc. Cancer Res. 1998 Jun 15;58(12):2612-7. Cancer Res. 1998. PMID: 9635587

2

Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.

Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I. Onda M, et al. Cancer Res. 2001 Jul 1;61(13):5070-7. Cancer Res. 2001. PMID: 11431343

3

Antitumor activity and pharmacokinetics in mice of a recombinant immunotoxin containing a disulfide-stabilized Fv fragment.

Reiter Y, Pai LH, Brinkmann U, Wang QC, Pastan I. Reiter Y, et al. Among authors: wang qc. Cancer Res. 1994 May 15;54(10):2714-8. Cancer Res. 1994. PMID: 8168102

4

Epitope blocking: positive and negative effects on the biodistribution of 125I-labeled anti-Tac disulfide-stabilized Fv fragment of two antibodies against different epitopes of the circulating antigen.

Kobayashi H, Sun BF, Han ES, Kim MK, Le N, Wang QC, Nelson DL, Pastan I, Waldmann TA, Paik CH, Carrasquillo JA. Kobayashi H, et al. Among authors: wang qc. Jpn J Cancer Res. 1998 Apr;89(4):436-44. doi: 10.1111/j.1349-7006.1998.tb00582.x. Jpn J Cancer Res. 1998. PMID: 9617350 Free PMC article.

5

Chemical modification to reduce renal uptake of disulfide-bonded variable region fragment of anti-Tac monoclonal antibody labeled with 99mTc.

Kim IS, Yoo TM, Kobayashi H, Kim MK, Le N, Wang QC, Pastan I, Carrasquillo JA, Paik CH. Kim IS, et al. Among authors: wang qc. Bioconjug Chem. 1999 May-Jun;10(3):447-53. doi: 10.1021/bc980129m. Bioconjug Chem. 1999. PMID: 10346877

6

Polyethylene glycol-modified chimeric toxin composed of transforming growth factor alpha and Pseudomonas exotoxin.

Wang QC, Pai LH, Debinski W, FitzGerald DJ, Pastan I. Wang QC, et al. Cancer Res. 1993 Oct 1;53(19):4588-94. Cancer Res. 1993. PMID: 8402632

7

Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys.

Kreitman RJ, Wang QC, FitzGerald DJ, Pastan I. Kreitman RJ, et al. Among authors: wang qc. Int J Cancer. 1999 Mar 31;81(1):148-55. doi: 10.1002/(sici)1097-0215(19990331)81:1<148::aid-ijc24>3.0.co;2-l. Int J Cancer. 1999. PMID: 10077166

8

Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) toward fresh malignant cells from patients with B-cell leukemias.

Kreitman RJ, Margulies I, Stetler-Stevenson M, Wang QC, FitzGerald DJ, Pastan I. Kreitman RJ, et al. Among authors: wang qc. Clin Cancer Res. 2000 Apr;6(4):1476-87. Clin Cancer Res. 2000. PMID: 10778980

9

Lowering of pI by acylation improves the renal uptake of 99mTc-labeled anti-Tac dsFv: effect of different acylating reagents.

Kim I, Kobayashi H, Yoo TM, Kim MK, Le N, Han ES, Wang QC, Pastan I, Carrasquillo JA, Paik CH. Kim I, et al. Among authors: wang qc. Nucl Med Biol. 2002 Nov;29(8):795-801. doi: 10.1016/s0969-8051(02)00341-4. Nucl Med Biol. 2002. PMID: 12453588

10

Eradication of tumor colonization and invasion by a B cell-specific immunotoxin in a murine model for human primary intraocular lymphoma.

Li Z, Mahesh SP, Shen DF, Liu B, Siu WO, Hwang FS, Wang QC, Chan CC, Pastan I, Nussenblatt RB. Li Z, et al. Among authors: wang qc. Cancer Res. 2006 Nov 1;66(21):10586-93. doi: 10.1158/0008-5472.CAN-06-1981. Cancer Res. 2006. PMID: 17079483 Free PMC article.

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