Smyth MJ - Search Results

1

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis.

Smyth MJ, Krasovskis E, Sutton VR, Johnstone RW. Smyth MJ, et al. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7024-9. doi: 10.1073/pnas.95.12.7024. Proc Natl Acad Sci U S A. 1998. PMID: 9618532 Free PMC article.

2

Xenospecific cytotoxic T lymphocytes use perforin- and Fas-mediated lytic pathways.

Smyth MJ, Sutton VR, Kershaw MH, Trapani JA. Smyth MJ, et al. Transplantation. 1996 Nov 27;62(10):1529-32. doi: 10.1097/00007890-199611270-00030. Transplantation. 1996. PMID: 8958289

3

Fas ligand-mediated lysis of self bystander targets by human papillomavirus-specific CD8+ cytotoxic T lymphocytes.

Smyth MJ, Krasovskis E, Johnstone RW. Smyth MJ, et al. J Virol. 1998 Jul;72(7):5948-54. doi: 10.1128/JVI.72.7.5948-5954.1998. J Virol. 1998. PMID: 9621057 Free PMC article.

4

Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent.

Trapani JA, Jans DA, Jans PJ, Smyth MJ, Browne KA, Sutton VR. Trapani JA, et al. Among authors: smyth mj. J Biol Chem. 1998 Oct 23;273(43):27934-8. doi: 10.1074/jbc.273.43.27934. J Biol Chem. 1998. PMID: 9774406 Free article.

5

P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death.

Johnstone RW, Cretney E, Smyth MJ. Johnstone RW, et al. Among authors: smyth mj. Blood. 1999 Feb 1;93(3):1075-85. Blood. 1999. PMID: 9920858 Free article.

6

Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction.

Trapani JA, Jans P, Smyth MJ, Froelich CJ, Williams EA, Sutton VR, Jans DA. Trapani JA, et al. Among authors: smyth mj. Cell Death Differ. 1998 Jun;5(6):488-96. doi: 10.1038/sj.cdd.4400373. Cell Death Differ. 1998. PMID: 10200500

7

Multiple deficiencies underlie NK cell inactivity in lymphotoxin-alpha gene-targeted mice.

Smyth MJ, Johnstone RW, Cretney E, Haynes NM, Sedgwick JD, Korner H, Poulton LD, Baxter AG. Smyth MJ, et al. J Immunol. 1999 Aug 1;163(3):1350-3. J Immunol. 1999. PMID: 10415034

8

CTL granules: evolution of vesicles essential for combating virus infections.

Trapani JA, Sutton VR, Smyth MJ. Trapani JA, et al. Among authors: smyth mj. Immunol Today. 1999 Aug;20(8):351-6. doi: 10.1016/s0167-5699(99)01488-7. Immunol Today. 1999. PMID: 10431154 Review.

9

Multiple physiological functions for multidrug transporter P-glycoprotein?

Johnstone RW, Ruefli AA, Smyth MJ. Johnstone RW, et al. Among authors: smyth mj. Trends Biochem Sci. 2000 Jan;25(1):1-6. doi: 10.1016/s0968-0004(99)01493-0. Trends Biochem Sci. 2000. PMID: 10637601 Review.

10

HMBA induces activation of a caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance.

Ruefli AA, Smyth MJ, Johnstone RW. Ruefli AA, et al. Among authors: smyth mj. Blood. 2000 Apr 1;95(7):2378-85. Blood. 2000. PMID: 10733510 Free article.

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