DeBrabander J - Search Results

1

The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1.

Wender PA, DeBrabander J, Harran PG, Jimenez JM, Koehler MF, Lippa B, Park CM, Siedenbiedel C, Pettit GR. Wender PA, et al. Among authors: debrabander j. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6624-9. doi: 10.1073/pnas.95.12.6624. Proc Natl Acad Sci U S A. 1998. PMID: 9618462 Free PMC article.

2

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death.

Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. Li L, et al. Science. 2004 Sep 3;305(5689):1471-4. doi: 10.1126/science.1098231. Science. 2004. PMID: 15353805

3

Triazoles inhibit cholesterol export from lysosomes by binding to NPC1.

Trinh MN, Lu F, Li X, Das A, Liang Q, De Brabander JK, Brown MS, Goldstein JL. Trinh MN, et al. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):89-94. doi: 10.1073/pnas.1619571114. Epub 2016 Dec 19. Proc Natl Acad Sci U S A. 2017. PMID: 27994139 Free PMC article.

4

An adipo-biliary-uridine axis that regulates energy homeostasis.

Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE. Deng Y, et al. Science. 2017 Mar 17;355(6330):eaaf5375. doi: 10.1126/science.aaf5375. Epub 2017 Mar 16. Science. 2017. PMID: 28302796 Free PMC article.

5

Synthesis and initial structure--activity relationships of modified salicylihalamides.

Wu Y, Seguil OR, De Brabander JK. Wu Y, et al. Org Lett. 2000 Dec 28;2(26):4241-4. doi: 10.1021/ol0068086. Org Lett. 2000. PMID: 11150209

6

Synthesis of psymberin analogues: probing a functional correlation with the pederin/mycalamide family of natural products.

Jiang X, Williams N, De Brabander JK. Jiang X, et al. Org Lett. 2007 Jan 18;9(2):227-30. doi: 10.1021/ol062656o. Org Lett. 2007. PMID: 17217271 Free PMC article.

7

Synthesis and complete stereochemical assignment of psymberin/irciniastatin A.

Jiang X, García-Fortanet J, De Brabander JK. Jiang X, et al. J Am Chem Soc. 2005 Aug 17;127(32):11254-5. doi: 10.1021/ja0537068. J Am Chem Soc. 2005. PMID: 16089449

8

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs.

Adams CM, Reitz J, De Brabander JK, Feramisco JD, Li L, Brown MS, Goldstein JL. Adams CM, et al. J Biol Chem. 2004 Dec 10;279(50):52772-80. doi: 10.1074/jbc.M410302200. Epub 2004 Sep 27. J Biol Chem. 2004. PMID: 15452130 Free article.

9

Synthesis and structure-activity studies of the V-ATPase inhibitor saliphenylhalamide (SaliPhe) and simplified analogs.

Garcia-Rodriguez J, Mendiratta S, White MA, Xie XS, De Brabander JK. Garcia-Rodriguez J, et al. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4393-8. doi: 10.1016/j.bmcl.2015.09.021. Epub 2015 Sep 8. Bioorg Med Chem Lett. 2015. PMID: 26372654

10

Synthesis of functionalized salicylate esters and amides by photochemical acylation.

Soltani O, De Brabander JK. Soltani O, et al. Angew Chem Int Ed Engl. 2005 Mar 4;44(11):1696-9. doi: 10.1002/anie.200462577. Angew Chem Int Ed Engl. 2005. PMID: 15685672 No abstract available.

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