Dickins M - Search Results

1

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily.

Lewis DF, Dickins M, Weaver RJ, Eddershaw PJ, Goldfarb PS, Tarbit MH. Lewis DF, et al. Among authors: dickins m. Xenobiotica. 1998 Mar;28(3):235-68. doi: 10.1080/004982598239542. Xenobiotica. 1998. PMID: 9574814

2

Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate.

Lewis DF, Eddershaw PJ, Dickins M, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Chem Biol Interact. 1998 Oct 2;115(3):175-99. doi: 10.1016/s0009-2797(98)00068-4. Chem Biol Interact. 1998. PMID: 9851289 Review.

3

Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4.

Lewis DF, Lake BG, Dickins M, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Xenobiotica. 1999 Apr;29(4):361-93. doi: 10.1080/004982599238560. Xenobiotica. 1999. PMID: 10375007

4

Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity.

Lewis DF, Dickins M, Lake BG, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Toxicology. 1999 Mar 1;133(1):1-33. doi: 10.1016/s0300-483x(98)00149-8. Toxicology. 1999. PMID: 10413191

5

Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102.

Lewis DF, Lake BG, George SG, Dickins M, Eddershaw PJ, Tarbit MH, Beresford AP, Goldfarb PS, Guengerich FP. Lewis DF, et al. Among authors: dickins m. Toxicology. 1999 Nov 29;139(1-2):53-79. doi: 10.1016/s0300-483x(99)00098-0. Toxicology. 1999. PMID: 10614688

6

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform.

Lewis DF, Bird MG, Dickins M, Lake BG, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Xenobiotica. 2000 Jan;30(1):1-25. doi: 10.1080/004982500237794. Xenobiotica. 2000. PMID: 10659948

7

Cytochrome P450 substrate specificities, substrate structural templates and enzyme active site geometries.

Lewis DF, Dickins M, Eddershaw PJ, Tarbit MH, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Drug Metabol Drug Interact. 1999;15(1):1-49. doi: 10.1515/dmdi.1999.15.1.1. Drug Metabol Drug Interact. 1999. PMID: 10707112 Review.

8

Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme-substrate and enzyme-inhibitor interactions.

Lewis DF, Lake BG, Bird MG, Loizou GD, Dickins M, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Toxicol In Vitro. 2003 Feb;17(1):93-105. doi: 10.1016/s0887-2333(02)00098-x. Toxicol In Vitro. 2003. PMID: 12537967

9

Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure.

Lewis DF, Lake BG, Dickins M, Ueng YF, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Xenobiotica. 2003 Mar;33(3):239-54. doi: 10.1080/0049825021000048791. Xenobiotica. 2003. PMID: 12637242

10

Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme-substrate interactions and QSARs for binding affinity and inhibition.

Lewis DF, Lake BG, Dickins M, Goldfarb PS. Lewis DF, et al. Among authors: dickins m. Toxicol In Vitro. 2003 Apr;17(2):179-90. doi: 10.1016/s0887-2333(02)00132-7. Toxicol In Vitro. 2003. PMID: 12650672

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

84 results

Search Page

Filters