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The discovery of LY293111, a novel, potent and orally active leukotriene B4 receptor antagonist of the biphenylphenol class.
Sofia MJ, Floreancig P, Bach N, Baker SR, Nelson K, Sawyer JS, Baldwin R, Cockerham SL, Fleisch JH, Froelich LL, Jackson WT, Marder P, Roman CR, Saussy DL Jr, Silbaugh SA, Spaethe SM, Stengel PW. Sofia MJ, et al. Among authors: roman cr. Adv Exp Med Biol. 1997;400A:381-6. doi: 10.1007/978-1-4615-5325-0_51. Adv Exp Med Biol. 1997. PMID: 9547580 No abstract available.
Pulmonary actions of LY255283, a leukotriene B4 receptor antagonist.
Silbaugh SA, Stengel PW, Cockerham SL, Roman CR, Saussy DL Jr, Spaethe SM, Goodson T Jr, Herron DK, Fleisch JH. Silbaugh SA, et al. Among authors: roman cr. Eur J Pharmacol. 1992 Nov 13;223(1):57-64. doi: 10.1016/0014-2999(92)90818-o. Eur J Pharmacol. 1992. PMID: 1335877
o-phenylphenols: potent and orally active leukotriene B4 receptor antagonists.
Sofia MJ, Floreancig P, Bach NJ, Baker SR, Cockerham SL, Fleisch JH, Froelich LL, Jackson WT, Marder P, Roman CR, et al. Sofia MJ, et al. Among authors: roman cr. J Med Chem. 1993 Nov 26;36(24):3978-81. doi: 10.1021/jm00076a029. J Med Chem. 1993. PMID: 7902871 No abstract available.
Contraction of guinea pig inferior vena cava by eicosanoids.
Rinkema LE, Roman CR, VanAlstyne EL, Spaethe SM, Fleisch JH. Rinkema LE, et al. Among authors: roman cr. Naunyn Schmiedebergs Arch Pharmacol. 1993 Nov;348(5):520-5. doi: 10.1007/BF00173213. Naunyn Schmiedebergs Arch Pharmacol. 1993. PMID: 8114952
35 results