Gleason JG - Search Results

1

1,4-Cyclohexanecarboxylates: potent and selective inhibitors of phosophodiesterase 4 for the treatment of asthma.

Christensen SB, Guider A, Forster CJ, Gleason JG, Bender PE, Karpinski JM, DeWolf WE Jr, Barnette MS, Underwood DC, Griswold DE, Cieslinski LB, Burman M, Bochnowicz S, Osborn RR, Manning CD, Grous M, Hillegas LM, Bartus JO, Ryan MD, Eggleston DS, Haltiwanger RC, Torphy TJ. Christensen SB, et al. Among authors: gleason jg. J Med Chem. 1998 Mar 12;41(6):821-35. doi: 10.1021/jm970090r. J Med Chem. 1998. PMID: 9526558

2

The preclinical and clinical pharmacology of SK&F 104353, a potent and selective peptidoleukotriene receptor antagonist.

Torphy TJ, Faiferman I, Gleason JG, Hall RF, Lewis MA, Broom C, Helfrich HM, Newton JF, Hay DW. Torphy TJ, et al. Among authors: gleason jg. Ann N Y Acad Sci. 1991;629:157-67. doi: 10.1111/j.1749-6632.1991.tb37973.x. Ann N Y Acad Sci. 1991. PMID: 1659277 Review. No abstract available.

3

Pharmacologic and pharmacokinetic profile of SK&F S-106203, a potent, orally active peptidoleukotriene receptor antagonist, in guinea-pig.

Hay DW, Muccitelli RM, Vickery-Clark LM, Novak LS, Osborn RR, Gleason JG, Yodis LA, Saverino CM, Eckardt RD, Sarau HM, et al. Hay DW, et al. Among authors: gleason jg. Pulm Pharmacol. 1991;4(3):177-89. doi: 10.1016/0952-0600(91)90009-r. Pulm Pharmacol. 1991. PMID: 1668219

4

Pharmacologic profile of SK&F 104353: a novel, potent and selective peptidoleukotriene receptor antagonist in guinea pig and human airways.

Hay DW, Muccitelli RM, Tucker SS, Vickery-Clark LM, Wilson KA, Gleason JG, Hall RF, Wasserman MA, Torphy TJ. Hay DW, et al. Among authors: gleason jg. J Pharmacol Exp Ther. 1987 Nov;243(2):474-81. J Pharmacol Exp Ther. 1987. PMID: 2824747

5

1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists.

Weinstock J, Keenan RM, Samanen J, Hempel J, Finkelstein JA, Franz RG, Gaitanopoulos DE, Girard GR, Gleason JG, Hill DT, et al. Weinstock J, et al. Among authors: gleason jg. J Med Chem. 1991 Apr;34(4):1514-7. doi: 10.1021/jm00108a043. J Med Chem. 1991. PMID: 2016730 No abstract available.

6

Synthesis and LTB4 receptor antagonist activities of the naturally occurring LTB4 receptor antagonist Leucettamine A and related analogues.

Boehm JC, Gleason JG, Pendrak I, Sarau HM, Schmidt DB, Foley JJ, Kingsbury WD. Boehm JC, et al. Among authors: gleason jg. J Med Chem. 1993 Oct 29;36(22):3333-40. doi: 10.1021/jm00074a014. J Med Chem. 1993. PMID: 8230123

7

Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P1'--P2' amide bond isostere.

Thompson SK, Murthy KH, Zhao B, Winborne E, Green DW, Fisher SM, DesJarlais RL, Tomaszek TA Jr, Meek TD, Gleason JG, et al. Thompson SK, et al. Among authors: gleason jg. J Med Chem. 1994 Sep 16;37(19):3100-7. doi: 10.1021/jm00045a015. J Med Chem. 1994. PMID: 7932533

8

Structural requirements for chemotactic activity of leukotriene B4 (LTB4).

Hoffstein ST, Manzi RM, Razgaitis KA, Bender PE, Gleason J. Hoffstein ST, et al. Prostaglandins. 1986 Feb;31(2):205-15. doi: 10.1016/0090-6980(86)90047-x. Prostaglandins. 1986. PMID: 3008215

9

Antagonism of the pulmonary effects of the peptidoleukotrienes by a leukotriene D4 analog.

Weichman BM, Wasserman MA, Holden DA, Osborn RR, Woodward DF, Ku TW, Gleason JG. Weichman BM, et al. Among authors: gleason jg. J Pharmacol Exp Ther. 1983 Dec;227(3):700-5. J Pharmacol Exp Ther. 1983. PMID: 6655563

10

Design of potent and selective human cathepsin K inhibitors that span the active site.

Thompson SK, Halbert SM, Bossard MJ, Tomaszek TA, Levy MA, Zhao B, Smith WW, Abdel-Meguid SS, Janson CA, D'Alessio KJ, McQueney MS, Amegadzie BY, Hanning CR, DesJarlais RL, Briand J, Sarkar SK, Huddleston MJ, Ijames CF, Carr SA, Garnes KT, Shu A, Heys JR, Bradbeer J, Zembryki D, Lee-Rykaczewski L, James IE, Lark MW, Drake FH, Gowen M, Gleason JG, Veber DF. Thompson SK, et al. Among authors: gleason jg. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14249-54. doi: 10.1073/pnas.94.26.14249. Proc Natl Acad Sci U S A. 1997. PMID: 9405598 Free PMC article.

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