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Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection.
Mendel DB, Tai CY, Escarpe PA, Li W, Sidwell RW, Huffman JH, Sweet C, Jakeman KJ, Merson J, Lacy SA, Lew W, Williams MA, Zhang L, Chen MS, Bischofberger N, Kim CU. Mendel DB, et al. Among authors: lacy sa. Antimicrob Agents Chemother. 1998 Mar;42(3):640-6. doi: 10.1128/AAC.42.3.640. Antimicrob Agents Chemother. 1998. PMID: 9517945 Free PMC article.
1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo.
Bischofberger N, Hitchcock MJ, Chen MS, Barkhimer DB, Cundy KC, Kent KM, Lacy SA, Lee WA, Li ZH, Mendel DB, et al. Bischofberger N, et al. Among authors: lacy sa. Antimicrob Agents Chemother. 1994 Oct;38(10):2387-91. doi: 10.1128/AAC.38.10.2387. Antimicrob Agents Chemother. 1994. PMID: 7840575 Free PMC article.
Assessment of cabozantinib treatment on QT interval in a phase 3 study in medullary thyroid cancer: evaluation of indirect QT effects mediated through treatment-induced changes in serum electrolytes.
Miles DR, Lacy SA, Wada DR, Milwee S, Yaron Y, Nguyen LT. Miles DR, et al. Among authors: lacy sa. Cancer Chemother Pharmacol. 2017 Aug;80(2):295-306. doi: 10.1007/s00280-017-3349-y. Epub 2017 Jun 20. Cancer Chemother Pharmacol. 2017. PMID: 28634649 Clinical Trial.
15 results