Hudson K - Search Results

1

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: hudson k. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

2

A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr(286), not Thr(288).

Ashford AL, Oxley D, Kettle J, Hudson K, Guichard S, Cook SJ, Lochhead PA. Ashford AL, et al. Among authors: hudson k. Biochem J. 2014 Jan 1;457(1):43-56. doi: 10.1042/BJ20130461. Biochem J. 2014. PMID: 24134204

3

A tandem pair of Leishmania donovani cation transporting ATPase genes encode isoforms that are differentially expressed.

Meade JC, Hudson KM, Stringer SL, Stringer JR. Meade JC, et al. Among authors: hudson km. Mol Biochem Parasitol. 1989 Feb;33(1):81-91. doi: 10.1016/0166-6851(89)90045-5. Mol Biochem Parasitol. 1989. PMID: 2469011

4

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.

Ashford AL, Dunkley TP, Cockerill M, Rowlinson RA, Baak LM, Gallo R, Balmanno K, Goodwin LM, Ward RA, Lochhead PA, Guichard S, Hudson K, Cook SJ. Ashford AL, et al. Among authors: hudson k. Cell Mol Life Sci. 2016 Feb;73(4):883-900. doi: 10.1007/s00018-015-2032-x. Epub 2015 Sep 7. Cell Mol Life Sci. 2016. PMID: 26346493 Free PMC article.

5

Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis.

Kettle JG, Ballard P, Bardelle C, Cockerill M, Colclough N, Critchlow SE, Debreczeni J, Fairley G, Fillery S, Graham MA, Goodwin L, Guichard S, Hudson K, Ward RA, Whittaker D. Kettle JG, et al. Among authors: hudson k. J Med Chem. 2015 Mar 26;58(6):2834-44. doi: 10.1021/acs.jmedchem.5b00098. Epub 2015 Mar 12. J Med Chem. 2015. PMID: 25738750

6

PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4⁺ T Cells.

Luff DH, Wojdyla K, Oxley D, Chessa T, Hudson K, Hawkins PT, Stephens LR, Barry ST, Okkenhaug K. Luff DH, et al. Among authors: hudson k. Front Immunol. 2021 Mar 8;12:631271. doi: 10.3389/fimmu.2021.631271. eCollection 2021. Front Immunol. 2021. PMID: 33763075 Free PMC article.

7

A new series of neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase.

Barlaam B, Ballard P, Bradbury RH, Ducray R, Germain H, Hickinson DM, Hudson K, Kettle JG, Klinowska T, Magnien F, Ogilvie DJ, Olivier A, Pearson SE, Scott JS, Suleman A, Trigwell CB, Vautier M, Whittaker RD, Wood R. Barlaam B, et al. Among authors: hudson k. Bioorg Med Chem Lett. 2008 Jan 15;18(2):674-8. doi: 10.1016/j.bmcl.2007.11.052. Epub 2007 Nov 21. Bioorg Med Chem Lett. 2008. PMID: 18061446

8

Sequence from ribosomal RNA of Pneumocystis carinii compared to those of four fungi suggests an ascomycetous affinity.

Stringer SL, Hudson K, Blase MA, Walzer PD, Cushion MT, Stringer JR. Stringer SL, et al. Among authors: hudson k. J Protozool. 1989 Jan-Feb;36(1):14S-16S. doi: 10.1111/j.1550-7408.1989.tb02670.x. J Protozool. 1989. PMID: 2785181 No abstract available.

9

Identification of altered gene expression in skeletal muscle during sepsis using differential display.

Tiao GM, Hudson K, Lieberman MA, Fischer JE, Hasselgren PO. Tiao GM, et al. Among authors: hudson k. J Surg Res. 1996 Jul 15;64(1):63-7. doi: 10.1006/jsre.1996.0307. J Surg Res. 1996. PMID: 8806475

10

Enzymatic characterisation of USP7 deubiquitinating activity and inhibition.

Wrigley JD, Eckersley K, Hardern IM, Millard L, Walters M, Peters SW, Mott R, Nowak T, Ward RA, Simpson PB, Hudson K. Wrigley JD, et al. Among authors: hudson k. Cell Biochem Biophys. 2011 Jun;60(1-2):99-111. doi: 10.1007/s12013-011-9186-4. Cell Biochem Biophys. 2011. PMID: 21468692

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