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Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1.
Kurth V, Ogorek I, Münch C, Lopez-Rios J, Ousson S, Lehmann S, Nieweg K, Roebroek AJM, Pietrzik CU, Beher D, Weggen S. Kurth V, et al. Among authors: weggen s. J Biol Chem. 2023 Aug;299(8):104997. doi: 10.1016/j.jbc.2023.104997. Epub 2023 Jun 30. J Biol Chem. 2023. PMID: 37394008 Free PMC article.
Migratory potential of transplantable neural tumor cell lines.
Bayer TA, Thier M, Roeb E, Breuer B, Weggen S, Wiestler OD, Weis J. Bayer TA, et al. Among authors: weggen s. Acta Neuropathol. 1999 Jun;97(6):607-12. doi: 10.1007/s004010051036. Acta Neuropathol. 1999. PMID: 10378379
89 results