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Slow-phase kinetics of nucleotide binding to the uncoupling protein from brown adipose tissue mitochondria.
Huang SG, Lin QS, Klingenberg M. Huang SG, et al. Among authors: klingenberg m. J Biol Chem. 1998 Jan 9;273(2):859-64. doi: 10.1074/jbc.273.2.859. J Biol Chem. 1998. PMID: 9422742 Free article.
Fast and slow phases of binding were observed, corresponding to the two-stage binding model based on equilibrium binding studies (Huang, S. G., and Klingenberg, M. (1996) Biochemistry 35, 7846-7854) (Reaction 1). [reaction: see text] Although this method determines …
Fast and slow phases of binding were observed, corresponding to the two-stage binding model based on equilibrium binding studies (Huang, S. …
ADP/ATP carrier and uncoupling protein.
Klingenberg M, Winkler E, Huang S. Klingenberg M, et al. Methods Enzymol. 1995;260:369-89. doi: 10.1016/0076-6879(95)60151-1. Methods Enzymol. 1995. PMID: 8592460 No abstract available.
Two-stage nucleotide binding mechanism and its implications to H+ transport inhibition of the uncoupling protein from brown adipose tissue mitochondria.
Huang SG, Klingenberg M. Huang SG, et al. Among authors: klingenberg m. Biochemistry. 1996 Jun 18;35(24):7846-54. doi: 10.1021/bi960244p. Biochemistry. 1996. PMID: 8672485
Nucleotide binding again is strongly influenced by the pH [Klingenberg, M. (1988) Biochemistry 27, 781-791]. Previously, by using fluorescent 2'-O-dansyl (DANS) derivatives of purine nucleotides, a two-stage binding mechanism was unraveled with a slow transition fro …
Nucleotide binding again is strongly influenced by the pH [Klingenberg, M. (1988) Biochemistry 27, 781-791]. Previously, by us …
Chloride channel properties of the uncoupling protein from brown adipose tissue mitochondria: a patch-clamp study.
Huang SG, Klingenberg M. Huang SG, et al. Among authors: klingenberg m. Biochemistry. 1996 Dec 24;35(51):16806-14. doi: 10.1021/bi960989v. Biochemistry. 1996. PMID: 8988019
The uncoupling protein (UCP) from brown adipose tissue mitochondria possesses H+ and Cl- transport activities [reviewed in Klingenberg, M. (1990) Trends Biochem. Sci. 15, 108-112]. Being a member of a mitochondrial carrier family, the transport of H+ and Cl- is carr …
The uncoupling protein (UCP) from brown adipose tissue mitochondria possesses H+ and Cl- transport activities [reviewed in Klingenberg …
Structure-function relationship in UCP1.
Klingenberg M, Echtay KS, Bienengraeber M, Winkler E, Huang SG. Klingenberg M, et al. Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 6:S24-9. doi: 10.1038/sj.ijo.0800939. Int J Obes Relat Metab Disord. 1999. PMID: 10454117 Review.
Chimers of two fused ADP/ATP carrier monomers indicate a single channel for ADP/ATP transport.
Huang SG, Odoy S, Klingenberg M. Huang SG, et al. Among authors: klingenberg m. Arch Biochem Biophys. 2001 Oct 1;394(1):67-75. doi: 10.1006/abbi.2001.2520. Arch Biochem Biophys. 2001. PMID: 11566029
These results favor a single binding center gated pore model [Klingenberg, M. (1991) in A Study of Enzymes, Vol. 2: pp. 367-388] in which two AAC subunits cooperate for a coordinated ADP/ATP exchange through a single channel....
These results favor a single binding center gated pore model [Klingenberg, M. (1991) in A Study of Enzymes, Vol. 2: pp. 367-38 …
271 results