Rock KL - Search Results

1

Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide.

Craiu A, Akopian T, Goldberg A, Rock KL. Craiu A, et al. Among authors: rock kl. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10850-5. doi: 10.1073/pnas.94.20.10850. Proc Natl Acad Sci U S A. 1997. PMID: 9380723 Free PMC article.

2

Post-proteasomal antigen processing for major histocompatibility complex class I presentation.

Rock KL, York IA, Goldberg AL. Rock KL, et al. Nat Immunol. 2004 Jul;5(7):670-7. doi: 10.1038/ni1089. Nat Immunol. 2004. PMID: 15224092 Review.

3

Role of proteasomes in antigen presentation.

Gaczynska M, Rock KL, Goldberg AL. Gaczynska M, et al. Among authors: rock kl. Enzyme Protein. 1993;47(4-6):354-69. doi: 10.1159/000468693. Enzyme Protein. 1993. PMID: 7697133 Review.

4

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

Gaczynska M, Rock KL, Spies T, Goldberg AL. Gaczynska M, et al. Among authors: rock kl. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9213-7. doi: 10.1073/pnas.91.20.9213. Proc Natl Acad Sci U S A. 1994. PMID: 7937744 Free PMC article.

5

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.

Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL. Rock KL, et al. Cell. 1994 Sep 9;78(5):761-71. doi: 10.1016/s0092-8674(94)90462-6. Cell. 1994. PMID: 8087844

6

Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation.

Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Craiu A, et al. Among authors: rock kl. J Biol Chem. 1997 May 16;272(20):13437-45. doi: 10.1074/jbc.272.20.13437. J Biol Chem. 1997. PMID: 9148969 Free article.

7

Sequences that flank subdominant and cryptic epitopes influence the proteolytic generation of MHC class I-presented peptides.

Mo AX, van Lelyveld SF, Craiu A, Rock KL. Mo AX, et al. Among authors: rock kl. J Immunol. 2000 Apr 15;164(8):4003-10. doi: 10.4049/jimmunol.164.8.4003. J Immunol. 2000. PMID: 10754291

8

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase.

Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL. Saric T, et al. Among authors: rock kl. J Biol Chem. 2001 Sep 28;276(39):36474-81. doi: 10.1074/jbc.M105517200. Epub 2001 Jul 30. J Biol Chem. 2001. PMID: 11479311 Free article.

9

Protein degradation and the generation of MHC class I-presented peptides.

Rock KL, York IA, Saric T, Goldberg AL. Rock KL, et al. Adv Immunol. 2002;80:1-70. doi: 10.1016/s0065-2776(02)80012-8. Adv Immunol. 2002. PMID: 12078479 Review.

10

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

Goldberg AL, Cascio P, Saric T, Rock KL. Goldberg AL, et al. Among authors: rock kl. Mol Immunol. 2002 Oct;39(3-4):147-64. doi: 10.1016/s0161-5890(02)00098-6. Mol Immunol. 2002. PMID: 12200047 Review.

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