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Page 1
Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis.
Abruzzo GK, Flattery AM, Gill CJ, Kong L, Smith JG, Pikounis VB, Balkovec JM, Bouffard AF, Dropinski JF, Rosen H, Kropp H, Bartizal K. Abruzzo GK, et al. Among authors: bouffard af. Antimicrob Agents Chemother. 1997 Nov;41(11):2333-8. doi: 10.1128/AAC.41.11.2333. Antimicrob Agents Chemother. 1997. PMID: 9371329 Free PMC article.
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.
Singh SB, Ondeyka JG, Liu W, Chen S, Chen TS, Li X, Bouffard A, Dropinski J, Jones AB, McCormick S, Hayes N, Wang J, Sharma N, Macnaul K, Hernandez M, Chao YS, Baffic J, Lam MH, Burton C, Sparrow CP, Menke JG. Singh SB, et al. Among authors: bouffard a. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2824-8. doi: 10.1016/j.bmcl.2005.03.100. Bioorg Med Chem Lett. 2005. PMID: 15911262
CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML.
Silva H, Martin G, Birocchi F, Wehrli M, Kann MC, Supper VM, Parker A, Graham CE, Bratt AG, Bouffard AA, Donner H, Escobar G, Takei HN, Armstrong A, Goncalves S, Berger TR, Choi BD, Maus MV, Leick MB. Silva H, et al. Among authors: bouffard aa. Blood. 2024 Nov 21:blood.2023023210. doi: 10.1182/blood.2023023210. Online ahead of print. Blood. 2024. PMID: 39571145
P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell-Derived Cardiomyocytes in 3-Dimensional Suspension Culture Via FOXO-FOXM1 Regulation.
Velayutham N, Garbern JC, Elwell HLT, Zhuo Z, Rüland L, Elcure Alvarez F, Frontini S, Rodriguez Carreras Y, Eichholtz M, Ricci-Blair E, Shaw JY, Bouffard AH, Sokol M, Mancheño Juncosa E, Rhoades S, van den Berg D, Kreymerman A, Aoyama J, Höfflin J, Ryan H, Ho Sui S, Lee RT. Velayutham N, et al. Among authors: bouffard ah. J Am Heart Assoc. 2024 Jul 2;13(13):e033155. doi: 10.1161/JAHA.123.033155. Epub 2024 Jun 27. J Am Heart Assoc. 2024. PMID: 38934864 Free PMC article.
Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics.
Korell F, Olson ML, Salas-Benito D, Leick MB, Larson RC, Bouffard A, Silva H, Gasparetto A, Berger TR, Kann MC, Mergen M, Kienka T, Wehrli M, Haradhvala NJ, Bailey SR, Letai A, Maus MV. Korell F, et al. Among authors: bouffard a. Sci Transl Med. 2024 Jun 5;16(750):eadk7640. doi: 10.1126/scitranslmed.adk7640. Epub 2024 Jun 5. Sci Transl Med. 2024. PMID: 38838132
Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37+ lymphoid malignancies.
Frigault MJ, Graham CE, Berger TR, Ritchey J, Horick NK, El-Jawahri A, Scarfò I, Schmidts A, Haradhvala NJ, Wehrli M, Lee WH, Parker AL, Wiggin HR, Bouffard A, Dey A, Leick MB, Katsis K, Elder EL, Dolaher MA, Cook DT, Chekmasova AA, Huang L, Nikiforow S, Daley H, Ritz J, Armant M, Preffer F, DiPersio JF, Nardi V, Chen YB, Gallagher KME, Maus MV. Frigault MJ, et al. Among authors: bouffard a. Blood. 2024 Sep 12;144(11):1153-1167. doi: 10.1182/blood.2024024104. Blood. 2024. PMID: 38781564 Clinical Trial.
Correction: Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19.
Ormhøj M, Scarfò I, Cabral ML, Bailey SR, Lorrey SJ, Bouffard AA, Castano AP, Larson RC, Riley LS, Schmidts A, Choi BD, Andersen RS, Cédile O, Nyvold CG, Christensen JH, Gjerstorff MF, Ditzel HJ, Weinstock DM, Barington T, Frigault MJ, Maus MV. Ormhøj M, et al. Among authors: bouffard aa. Clin Cancer Res. 2024 May 15;30(10):2286. doi: 10.1158/1078-0432.CCR-24-1059. Clin Cancer Res. 2024. PMID: 38745479 No abstract available.
Stealth transgenes enable CAR-T cells to evade host immune responses.
Grauwet K, Berger T, Kann MC, Silva H, Larson R, Leick MB, Bailey SR, Bouffard AA, Millar D, Gallagher K, Turtle CJ, Frigault MJ, Maus MV. Grauwet K, et al. Among authors: bouffard aa. J Immunother Cancer. 2024 May 9;12(5):e008417. doi: 10.1136/jitc-2023-008417. J Immunother Cancer. 2024. PMID: 38724463 Free PMC article.
88 results