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Page 1
Characterization of the hydrolytic activity of a polyclonal catalytic antibody preparation by pH-dependence and chemical modification studies: evidence for the involvement of Tyr and Arg side chains as hydrogen-bond donors.
Resmini M, Vigna R, Simms C, Barber NJ, Hagi-Pavli EP, Watts AB, Verma C, Gallacher G, Brocklehurst K. Resmini M, et al. Among authors: gallacher g. Biochem J. 1997 Aug 15;326 ( Pt 1)(Pt 1):279-87. doi: 10.1042/bj3260279. Biochem J. 1997. PMID: 9337880 Free PMC article.
Improvement in hydrolytic antibody activity by change in haptenic structure from phosphate to phosphonate with retention of a common leaving-group determinant: evidence for the 'flexibility' hypothesis.
Gul S, Sonkaria S, Pinitglang S, Florez-Alvarez J, Hussain S, Thomas EW, Ostler EL, Gallacher G, Resmini M, Brocklehurst K. Gul S, et al. Among authors: gallacher g. Biochem J. 2003 Dec 15;376(Pt 3):813-21. doi: 10.1042/BJ20030716. Biochem J. 2003. PMID: 12946271 Free PMC article.
Evidence for 'lock and key' character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes.
Sonkaria S, Boucher G, Flórez-Olvarez J, Said B, Hussain S, Ostler EL, Gul S, Thomas EW, Resmini M, Gallacher G, Brocklehurst K. Sonkaria S, et al. Among authors: gallacher g. Biochem J. 2004 Jul 1;381(Pt 1):125-30. doi: 10.1042/BJ20031966. Biochem J. 2004. PMID: 15053743 Free PMC article.
Polyclonal antibody-catalysed amide hydrolysis.
Gallacher G, Searcey M, Jackson CS, Brocklehurst K. Gallacher G, et al. Biochem J. 1992 Jun 15;284 ( Pt 3)(Pt 3):675-80. doi: 10.1042/bj2840675. Biochem J. 1992. PMID: 1622388 Free PMC article.
Are polyclonal catalytic antibodies heterogeneous?
Carter S, Resmini M, Simms C, Sreedharan SK, Gallacher G, Brocklehurst K. Carter S, et al. Among authors: gallacher g. Biochem Soc Trans. 1997 Feb;25(1):86S. doi: 10.1042/bst025086s. Biochem Soc Trans. 1997. PMID: 9056984 No abstract available.
52 results