Hegi ME - Search Results

1

Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas.

Hegi ME, zur Hausen A, Rüedi D, Malin G, Kleihues P. Hegi ME, et al. Int J Cancer. 1997 Sep 26;73(1):57-63. doi: 10.1002/(sici)1097-0215(19970926)73:1<57::aid-ijc10>3.0.co;2-2. Int J Cancer. 1997. PMID: 9334810

2

Identical mutations of the p53 tumor suppressor gene in the gliomatous and the sarcomatous components of gliosarcomas suggest a common origin from glial cells.

Biernat W, Aguzzi A, Sure U, Grant JW, Kleihues P, Hegi ME. Biernat W, et al. Among authors: hegi me. J Neuropathol Exp Neurol. 1995 Sep;54(5):651-6. doi: 10.1097/00005072-199509000-00006. J Neuropathol Exp Neurol. 1995. PMID: 7666053

3

Familial brain tumour syndrome associated with a p53 germline deletion of codon 236.

Lübbe J, von Ammon K, Watanabe K, Hegi ME, Kleihues P. Lübbe J, et al. Among authors: hegi me. Brain Pathol. 1995 Jan;5(1):15-23. doi: 10.1111/j.1750-3639.1995.tb00572.x. Brain Pathol. 1995. PMID: 7767487

4

Determination of p53 mutations, EGFR overexpression, and loss of p16 expression in pediatric glioblastomas.

Sure U, Rüedi D, Tachibana O, Yonekawa Y, Ohgaki H, Kleihues P, Hegi ME. Sure U, et al. Among authors: hegi me. J Neuropathol Exp Neurol. 1997 Jul;56(7):782-9. J Neuropathol Exp Neurol. 1997. PMID: 9210874

5

Functional analyses of a unique p53 germline mutant (Y236delta) associated with a familial brain tumor syndrome.

Chène P, Ory K, Rüedi D, Soussi T, Hegi ME. Chène P, et al. Among authors: hegi me. Int J Cancer. 1999 Jul 2;82(1):17-22. doi: 10.1002/(sici)1097-0215(19990702)82:1<17::aid-ijc4>3.0.co;2-6. Int J Cancer. 1999. PMID: 10360814

6

p53 transdominance but no gain of function in mouse brain tumor model.

Hegi ME, Klein MA, Rüedi D, Chène P, Hamou MF, Aguzzi A. Hegi ME, et al. Cancer Res. 2000 Jun 1;60(11):3019-24. Cancer Res. 2000. PMID: 10850451

7

Reduced latency but no increased brain tumor penetrance in mice with astrocyte specific expression of a human p53 mutant.

Klein MA, Rüedi D, Nozaki M, Dell EW, Diserens AC, Seelentag W, Janzer RC, Aguzzi A, Hegi ME. Klein MA, et al. Among authors: hegi me. Oncogene. 2000 Nov 9;19(47):5329-37. doi: 10.1038/sj.onc.1203941. Oncogene. 2000. PMID: 11103934

8

Toward methylation-based classification of central nervous system tumors.

Hegi ME, Kleihues P, Wen PY, Suvà ML. Hegi ME, et al. Neuro Oncol. 2018 Apr 9;20(5):579-581. doi: 10.1093/neuonc/noy023. Neuro Oncol. 2018. PMID: 29584921 Free PMC article. No abstract available.

9

p53 gene mutation and ink4a-arf deletion appear to be two mutually exclusive events in human glioblastoma.

Fulci G, Labuhn M, Maier D, Lachat Y, Hausmann O, Hegi ME, Janzer RC, Merlo A, Van Meir EG. Fulci G, et al. Among authors: hegi me. Oncogene. 2000 Aug 3;19(33):3816-22. doi: 10.1038/sj.onc.1203700. Oncogene. 2000. PMID: 10949938

10

Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome.

Shnaper S, Desbaillets I, Brown DA, Murat A, Migliavacca E, Schluep M, Ostermann S, Hamou MF, Stupp R, Breit SN, de Tribolet N, Hegi ME. Shnaper S, et al. Among authors: hegi me. Int J Cancer. 2009 Dec 1;125(11):2624-30. doi: 10.1002/ijc.24639. Int J Cancer. 2009. PMID: 19521960

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