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beta2-chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain.
Caloca MJ, Garcia-Bermejo ML, Blumberg PM, Lewin NE, Kremmer E, Mischak H, Wang S, Nacro K, Bienfait B, Marquez VE, Kazanietz MG. Caloca MJ, et al. Among authors: lewin ne. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11854-9. doi: 10.1073/pnas.96.21.11854. Proc Natl Acad Sci U S A. 1999. PMID: 10518540 Free PMC article.
A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha.
Pu Y, Perry NA, Yang D, Lewin NE, Kedei N, Braun DC, Choi SH, Blumberg PM, Garfield SH, Stone JC, Duan D, Marquez VE. Pu Y, et al. Among authors: lewin ne. J Biol Chem. 2005 Jul 22;280(29):27329-38. doi: 10.1074/jbc.M414132200. Epub 2005 May 27. J Biol Chem. 2005. PMID: 15923197 Free article.
108 results