Sheppard GS - Search Results

1

ABT-491, a highly potent and selective PAF antagonist, inhibits nasal vascular permeability associated with experimental allergic rhinitis in brown Norway rats.

Albert DH, Tapang P, Morgan DW, Curtin ML, Sheppard GS, Davidsen SK, Summers JB, Carter GW. Albert DH, et al. Among authors: sheppard gs. Inflamm Res. 1997 Aug;46 Suppl 2:S133-4. doi: 10.1007/s000110050141. Inflamm Res. 1997. PMID: 9297547 No abstract available.

2

Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist.

Albert DH, Magoc TJ, Tapang P, Luo G, Morgan DW, Curtin M, Sheppard GS, Xu L, Heyman HR, Davidsen SK, Summers JB, Carter GW. Albert DH, et al. Among authors: sheppard gs. Eur J Pharmacol. 1997 Apr 23;325(1):69-80. doi: 10.1016/s0014-2999(97)00109-x. Eur J Pharmacol. 1997. PMID: 9151941

3

The role of platelet-activating factor (PAF) and the efficacy of ABT-491, a highly potent and selective PAF antagonist, in experimental allergic rhinitis.

Albert DH, Malo PE, Tapang P, Shaughnessy TK, Morgan DW, Wegner CD, Curtin ML, Sheppard GS, Xu L, Davidsen SK, Summers JB, Carter GW. Albert DH, et al. Among authors: sheppard gs. J Pharmacol Exp Ther. 1998 Jan;284(1):83-8. J Pharmacol Exp Ther. 1998. PMID: 9435164

4

3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists.

Sheppard GS, Pireh D, Carrera GM Jr, Bures MG, Heyman HR, Steinman DH, Davidsen SK, Phillips JG, Guinn DE, May PD, et al. Sheppard GS, et al. J Med Chem. 1994 Jun 24;37(13):2011-32. doi: 10.1021/jm00039a015. J Med Chem. 1994. PMID: 8027984

5

Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists.

Curtin ML, Davidsen SK, Heyman HR, Garland RB, Sheppard GS, Florjancic AS, Xu L, Carrera GM Jr, Steinman DH, Trautmann JA, Albert DH, Magoc TJ, Tapang P, Rhein DA, Conway RG, Luo G, Denissen JF, Marsh KC, Morgan DW, Summers JB. Curtin ML, et al. Among authors: sheppard gs. J Med Chem. 1998 Jan 1;41(1):74-95. doi: 10.1021/jm970389+. J Med Chem. 1998. PMID: 9438024

6

Aryl ketones as novel replacements for the C-terminal amide bond of succinyl hydroxamate MMP inhibitors.

Sheppard GS, Florjancic AS, Giesler JR, Xu L, Guo Y, Davidsen SK, Marcotte PA, Elmore I, Albert DH, Magoc TJ, Bouska JJ, Goodfellow CL, Morgan DW, Summers JB. Sheppard GS, et al. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3251-6. doi: 10.1016/s0960-894x(98)00597-6. Bioorg Med Chem Lett. 1998. PMID: 9873712

7

Evaluation of the inhibition of other metalloproteinases by matrix metalloproteinase inhibitors.

Marcotte PA, Elmore IN, Guan Z, Magoc TJ, Albert DH, Morgand DW, Curtin ML, Garland RB, Guo Y, Heyman HR, Holms JH, Sheppard GS, Steinman DH, Wada CK, Davidsen SK. Marcotte PA, et al. Among authors: sheppard gs. J Enzyme Inhib. 1999;14(6):425-35. doi: 10.3109/14756369909030333. J Enzyme Inhib. 1999. PMID: 10536876

8

Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2.

Wang J, Sheppard GS, Lou P, Kawai M, BaMaung N, Erickson SA, Tucker-Garcia L, Park C, Bouska J, Wang YC, Frost D, Tapang P, Albert DH, Morgan SJ, Morowitz M, Shusterman S, Maris JM, Lesniewski R, Henkin J. Wang J, et al. Among authors: sheppard gs. Cancer Res. 2003 Nov 15;63(22):7861-9. Cancer Res. 2003. PMID: 14633714

9

Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation.

Tucker LA, Zhang Q, Sheppard GS, Lou P, Jiang F, McKeegan E, Lesniewski R, Davidsen SK, Bell RL, Wang J. Tucker LA, et al. Among authors: sheppard gs. Oncogene. 2008 Jun 26;27(28):3967-76. doi: 10.1038/onc.2008.14. Epub 2008 Feb 11. Oncogene. 2008. PMID: 18264137

10

Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.

Wilsbacher JL, Zhang Q, Tucker LA, Hubbard RD, Sheppard GS, Bamaung NY, Fidanze SD, Wang GT, Hu X, Davidsen SK, Bell RL, Wang J. Wilsbacher JL, et al. Among authors: sheppard gs. J Biol Chem. 2008 Aug 29;283(35):23721-30. doi: 10.1074/jbc.M708360200. Epub 2008 Jun 17. J Biol Chem. 2008. PMID: 18559346 Free PMC article.

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