MacKenzie RG - Search Results

1

Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.

Unangst PC, Capiris T, Connor DT, Heffner TG, MacKenzie RG, Miller SR, Pugsley TA, Wise LD. Unangst PC, et al. Among authors: mackenzie rg. J Med Chem. 1997 Aug 15;40(17):2688-93. doi: 10.1021/jm970170v. J Med Chem. 1997. PMID: 9276014

2

The discovery and structure-activity relationships of 1,2,3,6-tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine autoreceptor agonists and potential antipsychotic agents.

Wright JL, Caprathe BW, Downing DM, Glase SA, Heffner TG, Jaen JC, Johnson SJ, Kesten SR, MacKenzie RG, Meltzer LT, et al. Wright JL, et al. Among authors: mackenzie rg. J Med Chem. 1994 Oct 14;37(21):3523-33. doi: 10.1021/jm00047a010. J Med Chem. 1994. PMID: 7932581

3

Studies of the active conformation of a novel series of benzamide dopamine D2 agonists.

Wustrow DJ, Wise LD, Cody DM, MacKenzie RG, Georgic LM, Pugsley TA, Heffner TG. Wustrow DJ, et al. Among authors: mackenzie rg. J Med Chem. 1994 Nov 25;37(24):4251-7. doi: 10.1021/jm00050a022. J Med Chem. 1994. PMID: 7990124

4

Identification, characterization and pharmacological profile of three metabolites of (R)-(+)-1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1- yl)methyl]pyridine (CI-1007), a dopamine autoreceptor agonist and potential antipsychotic agent.

Wright JL, Downing DM, Feng MR, Hayes RN, Heffner TG, MacKenzie RG, Meltzer LT, Pugsley TA, Wise LD. Wright JL, et al. Among authors: mackenzie rg. J Med Chem. 1995 Dec 22;38(26):5007-14. doi: 10.1021/jm00026a007. J Med Chem. 1995. PMID: 8544176

5

Aryl 1-but-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as potential antipsychotic agents: synthesis and structure-activity relationships.

Glase SA, Akunne HC, Heffner TG, Jaen JC, MacKenzie RG, Meltzer LT, Pugsley TA, Smith SJ, Wise LD. Glase SA, et al. Among authors: mackenzie rg. J Med Chem. 1996 Aug 2;39(16):3179-87. doi: 10.1021/jm950721m. J Med Chem. 1996. PMID: 8759640

6

Substituted [(4-phenylpiperazinyl)-methyl]benzamides: selective dopamine D4 agonists.

Glase SA, Akunne HC, Georgic LM, Heffner TG, MacKenzie RG, Manley PJ, Pugsley TA, Wise LD. Glase SA, et al. Among authors: mackenzie rg. J Med Chem. 1997 Jun 6;40(12):1771-2. doi: 10.1021/jm970021c. J Med Chem. 1997. PMID: 9191952 No abstract available.

7

(Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents.

Unangst PC, Capiris T, Connor DT, Doubleday R, Heffner TG, MacKenzie RG, Miller SR, Pugsley TA, Wise LD. Unangst PC, et al. Among authors: mackenzie rg. J Med Chem. 1997 Dec 5;40(25):4026-9. doi: 10.1021/jm970422s. J Med Chem. 1997. PMID: 9406594

8

PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects.

Akunne HC, Zoski KT, Davis MD, Cooke LW, Meltzer LT, Whetzel SZ, Shih YH, Wustrow DJ, Wise LD, MacKenzie RG, Georgic LM, Heffner TG, Pugsley TA. Akunne HC, et al. Among authors: mackenzie rg. Neuropharmacology. 2000 Apr 27;39(7):1197-210. doi: 10.1016/s0028-3908(99)00224-5. Neuropharmacology. 2000. PMID: 10760362

9

Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists.

Wustrow DJ, Capiris T, Rubin R, Knobelsdorf JA, Akunne H, Davis MD, MacKenzie R, Pugsley TA, Zoski KT, Heffner TG, Wise LD. Wustrow DJ, et al. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2067-70. doi: 10.1016/s0960-894x(98)00372-2. Bioorg Med Chem Lett. 1998. PMID: 9873487

10

The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists.

Pugsley TA, Shih YH, Whetzel SZ, Zoski K, Van Leeuwen D, Akunne H, Mackenzie R, Heffner TG, Wustrow D, Wise LD. Pugsley TA, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Feb;26(2):219-26. doi: 10.1016/s0278-5846(01)00252-4. Prog Neuropsychopharmacol Biol Psychiatry. 2002. PMID: 11817497

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