Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.
Nemes Z, Petrovski G, Aerts M, Sergeant K, Devreese B, Fésüs L.
Nemes Z, et al. Among authors: fesus l.
J Biol Chem. 2009 Oct 2;284(40):27252-64. doi: 10.1074/jbc.M109.033969. Epub 2009 Aug 3.
J Biol Chem. 2009.
PMID: 19651786
Free PMC article.
From the proteinase K-cleavable peripheral fraction of Lewy bodies, which was densely cross-linked by gamma-glutamyl-epsilon-lysine bonds between HspB1 and ubiquitin in a pattern similar to neurofibrillary tangles (Nemes, Z., Devreese, B., Steinert, P. M., Van Beeumen, J., and …
From the proteinase K-cleavable peripheral fraction of Lewy bodies, which was densely cross-linked by gamma-glutamyl-epsilon-lysine bonds be …