Chance RE - Search Results

1

Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor.

Slieker LJ, Brooke GS, DiMarchi RD, Flora DB, Green LK, Hoffmann JA, Long HB, Fan L, Shields JE, Sundell KL, Surface PL, Chance RE. Slieker LJ, et al. Among authors: chance re. Diabetologia. 1997 Jul;40 Suppl 2:S54-61. doi: 10.1007/s001250051402. Diabetologia. 1997. PMID: 9248702

2

Insulin and IGF-I analogs: novel approaches to improved insulin pharmacokinetics.

Slieker LJ, Brooke GS, Chance RE, Fan L, Hoffmann JA, Howey DC, Long HB, Mayer J, Shields JE, Sundell KL, et al. Slieker LJ, et al. Among authors: chance re. Adv Exp Med Biol. 1993;343:25-32. doi: 10.1007/978-1-4615-2988-0_3. Adv Exp Med Biol. 1993. PMID: 8184740 Review. No abstract available.

3

Preparation of an insulin with improved pharmacokinetics relative to human insulin through consideration of structural homology with insulin-like growth factor I.

DiMarchi RD, Chance RE, Long HB, Shields JE, Slieker LJ. DiMarchi RD, et al. Among authors: chance re. Horm Res. 1994;41 Suppl 2:93-6. doi: 10.1159/000183967. Horm Res. 1994. PMID: 8088710 Review.

4

Purification and analysis of the major components of chum salmon protamine contained in insulin formulations using high-performance liquid chromatography.

Hoffmann JA, Chance RE, Johnson MG. Hoffmann JA, et al. Among authors: chance re. Protein Expr Purif. 1990 Nov;1(2):127-33. doi: 10.1016/1046-5928(90)90005-j. Protein Expr Purif. 1990. PMID: 2136234

5

Self-association properties of monomeric insulin analogs under formulation conditions.

Richards JP, Stickelmeyer MP, Flora DB, Chance RE, Frank BH, DeFelippis MR. Richards JP, et al. Among authors: chance re. Pharm Res. 1998 Sep;15(9):1434-41. doi: 10.1023/a:1011961923870. Pharm Res. 1998. PMID: 9755897

6

Improved insulin stability through amino acid substitution.

Brems DN, Brown PL, Bryant C, Chance RE, Green LK, Long HB, Miller AA, Millican R, Shields JE, Frank BH. Brems DN, et al. Among authors: chance re. Protein Eng. 1992 Sep;5(6):519-25. doi: 10.1093/protein/5.6.519. Protein Eng. 1992. PMID: 1438162

7

Altering the association properties of insulin by amino acid replacement.

Brems DN, Alter LA, Beckage MJ, Chance RE, DiMarchi RD, Green LK, Long HB, Pekar AH, Shields JE, Frank BH. Brems DN, et al. Among authors: chance re. Protein Eng. 1992 Sep;5(6):527-33. doi: 10.1093/protein/5.6.527. Protein Eng. 1992. PMID: 1438163

8

Detection of an equilibrium intermediate in the folding of a monomeric insulin analog.

Bryant C, Strohl M, Green LK, Long HB, Alter LA, Pekar AH, Chance RE, Brems DN. Bryant C, et al. Among authors: chance re. Biochemistry. 1992 Jun 30;31(25):5692-8. doi: 10.1021/bi00140a002. Biochemistry. 1992. PMID: 1610818

9

(A-C-B) human proinsulin, a novel insulin agonist and intermediate in the synthesis of biosynthetic human insulin.

Heath WF, Belagaje RM, Brooke GS, Chance RE, Hoffmann JA, Long HB, Reams SG, Roundtree C, Shaw WN, Slieker LJ, et al. Heath WF, et al. Among authors: chance re. J Biol Chem. 1992 Jan 5;267(1):419-25. J Biol Chem. 1992. PMID: 1730606 Free article.

10

Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs--LysB28ProB29-human insulin and AspB10LysB28ProB29-human insulin--assessed in a conscious pig model.

Radziuk JM, Davies JC, Pye WS, Shields JE, DiMarchi RD, Chance RE. Radziuk JM, et al. Among authors: chance re. Diabetes. 1997 Apr;46(4):548-56. doi: 10.2337/diab.46.4.548. Diabetes. 1997. PMID: 9075793

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