Akizawa H - Search Results

1

Conventional and high-yield synthesis of DTPA-conjugated peptides: application of a monoreactive DTPA to DTPA-D-Phe1-octreotide synthesis.

Arano Y, Akizawa H, Uezono T, Akaji K, Ono M, Funakoshi S, Koizumi M, Yokoyama A, Kiso Y, Saji H. Arano Y, et al. Among authors: akizawa h. Bioconjug Chem. 1997 May-Jun;8(3):442-6. doi: 10.1021/bc970023b. Bioconjug Chem. 1997. PMID: 9177852

2

In vitro system to estimate renal brush border enzyme-mediated cleavage of Peptide linkages for designing radiolabeled antibody fragments of low renal radioactivity levels.

Fujioka Y, Satake S, Uehara T, Mukai T, Akizawa H, Ogawa K, Saji H, Endo K, Arano Y. Fujioka Y, et al. Among authors: akizawa h. Bioconjug Chem. 2005 Nov-Dec;16(6):1610-6. doi: 10.1021/bc050211z. Bioconjug Chem. 2005. PMID: 16287261

3

Reassessment of diethylenetriaminepentaacetic acid (DTPA) as a chelating agent for indium-111 labeling of polypeptides using a newly synthesized monoreactive DTPA derivative.

Arano Y, Uezono T, Akizawa H, Ono M, Wakisaka K, Nakayama M, Sakahara H, Konishi J, Yokoyama A. Arano Y, et al. Among authors: akizawa h. J Med Chem. 1996 Aug 30;39(18):3451-60. doi: 10.1021/jm950949+. J Med Chem. 1996. PMID: 8784442

4

Assessment of radiochemical design of antibodies using an ester bond as the metabolizable linkage: evaluation of maleimidoethyl 3-(tri-n-butylstannyl)hippurate as a radioiodination reagent of antibodies for diagnostic and therapeutic applications.

Arano Y, Wakisaka K, Ohmono Y, Uezono T, Akizawa H, Nakayama M, Sakahara H, Tanaka C, Konishi J, Yokoyama A. Arano Y, et al. Among authors: akizawa h. Bioconjug Chem. 1996 Nov-Dec;7(6):628-37. doi: 10.1021/bc960058w. Bioconjug Chem. 1996. PMID: 8950481

5

Renal metabolism of 111In-DTPA-D-Phe1-octreotide in vivo.

Akizawa H, Arano Y, Uezono T, Ono M, Fujioka Y, Uehara T, Yokoyama A, Akaji K, Kiso Y, Koizumi M, Saji H. Akizawa H, et al. Bioconjug Chem. 1998 Nov-Dec;9(6):662-70. doi: 10.1021/bc9702258. Bioconjug Chem. 1998. PMID: 9815158

6

Significance of (111)In-DTPA chelate in renal radioactivity levels of (111)In-DTPA-conjugated peptides.

Akizawa H, Arano Y, Mifune M, Iwado A, Saito Y, Uehara T, Ono M, Fujioka Y, Ogawa K, Kiso Y, Saji H. Akizawa H, et al. Nucl Med Biol. 2001 May;28(4):459-68. doi: 10.1016/s0969-8051(01)00207-4. Nucl Med Biol. 2001. PMID: 11395320

7

Effect of molecular charges on renal uptake of 111In-DTPA-conjugated peptides.

Akizawa H, Arano Y, Mifune M, Iwado A, Saito Y, Mukai T, Uehara T, Ono M, Fujioka Y, Ogawa K, Kiso Y, Saji H. Akizawa H, et al. Nucl Med Biol. 2001 Oct;28(7):761-8. doi: 10.1016/s0969-8051(01)00241-4. Nucl Med Biol. 2001. PMID: 11578896

8

Distribution and elimination characteristics of 111In-DTPA-D-phe1-octreotide and 111In-DTPA-L-phe1-octreotide in rats.

Laznickova A, Laznicek M, Trejtnar F, Melicharova L, Suzuki KH, Akizawa H, Arano Y, Yokoyama A. Laznickova A, et al. Among authors: akizawa h. Eur J Drug Metab Pharmacokinet. 2002 Jan-Mar;27(1):37-43. doi: 10.1007/BF03190403. Eur J Drug Metab Pharmacokinet. 2002. PMID: 11996325

9

Effect of carboxylation of N-terminal phenylalanine of (111)in-DTPA (diethylenetriaminepentaacetic acid)-octreotide on accumulation of radioactivity in kidney.

Akizawa H, Takimoto H, Saito M, Iwado A, Mifune M, Saito Y, Uehara T, Arano Y, Mukai T, Hanaoka H, Saji H. Akizawa H, et al. Biol Pharm Bull. 2004 Feb;27(2):271-2. doi: 10.1248/bpb.27.271. Biol Pharm Bull. 2004. PMID: 14758051 Free article.

10

Design, synthesis and biological evaluation of negatively charged ¹¹¹In-DTPA-octreotide derivatives.

Oshima N, Akizawa H, Zhao S, Zhao Y, Nishijima K, Kitamura Y, Arano Y, Kuge Y, Ohkura K. Oshima N, et al. Among authors: akizawa h. Bioorg Med Chem. 2014 Feb 15;22(4):1377-82. doi: 10.1016/j.bmc.2013.12.063. Epub 2014 Jan 8. Bioorg Med Chem. 2014. PMID: 24457092

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