Wachter M - Search Results

1

N-(5-substituted) thiophene-2-alkylsulfonamides as potent inhibitors of 5-lipoxygenase.

Beers SA, Malloy EA, Wu W, Wachter M, Ansell J, Singer M, Steber M, Barbone A, Kirchner T, Ritchie D, Argentieri D. Beers SA, et al. Among authors: wachter m. Bioorg Med Chem. 1997 Apr;5(4):779-86. doi: 10.1016/s0968-0896(97)00025-4. Bioorg Med Chem. 1997. PMID: 9158876

2

Synthesis and structure-activity relationships of 3,5-diarylisoxazoles and 3,5-diaryl-1,2,4-oxadiazoles, novel classes of small molecule interleukin-8 (IL-8) receptor antagonists.

Weidner-Wells MA, Henninger TC, Fraga-Spano SA, Boggs CM, Matheis M, Ritchie DM, Argentieri DC, Wachter MP, Hlasta DJ. Weidner-Wells MA, et al. Among authors: wachter mp. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4307-11. doi: 10.1016/j.bmcl.2004.05.080. Bioorg Med Chem Lett. 2004. PMID: 15261292

3

Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.

Argentieri DC, Ritchie DM, Ferro MP, Kirchner T, Wachter MP, Anderson DW, Rosenthale ME, Capetola RJ. Argentieri DC, et al. Among authors: wachter mp. J Pharmacol Exp Ther. 1994 Dec;271(3):1399-408. J Pharmacol Exp Ther. 1994. PMID: 7996452

4

Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.

Kirchner T, Argentieri DC, Barbone AG, Singer M, Steber M, Ansell J, Beers SA, Wachter MP, Wu W, Malloy E, Stewart A, Ritchie DM. Kirchner T, et al. Among authors: wachter mp. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101. J Pharmacol Exp Ther. 1997. PMID: 9262379

5

Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45.

Beers SA, Malloy EA, Wu W, Wachter MP, Gunnia U, Cavender D, Harris C, Davis J, Brosius R, Pellegrino-Gensey JL, Siekierka J. Beers SA, et al. Among authors: wachter mp. Bioorg Med Chem. 1997 Dec;5(12):2203-11. doi: 10.1016/s0968-0896(97)00174-0. Bioorg Med Chem. 1997. PMID: 9459018

6

N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase.

Connolly PJ, Wetter SK, Beers KN, Hamel SC, Chen RH, Wachter MP, Ansell J, Singer MM, Steber M, Ritchie DM, Argentieri DC. Connolly PJ, et al. Among authors: wachter mp. Bioorg Med Chem Lett. 1999 Apr 5;9(7):979-84. doi: 10.1016/s0960-894x(99)00117-1. Bioorg Med Chem Lett. 1999. PMID: 10230624

7

1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2.

Sui Z, Guan J, Ferro MP, McCoy K, Wachter MP, Murray WV, Singer M, Steber M, Ritchie DM, Argentieri DC. Sui Z, et al. Among authors: wachter mp. Bioorg Med Chem Lett. 2000 Mar 20;10(6):601-4. doi: 10.1016/s0960-894x(00)00041-x. Bioorg Med Chem Lett. 2000. PMID: 10741562

8

Substituted dipiperidine alcohols as potent CCR2 antagonists.

Xia M, Hou C, Demong D, Pollack S, Pan M, Brackley J, Singer M, Matheis M, Cavender D, Wachter M. Xia M, et al. Among authors: wachter m. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3562-4. doi: 10.1016/j.bmcl.2008.05.010. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18487045

9

Design, synthesis, and biological activity of diiminoisoindolines as complement component 3a antagonists.

Grant EB, Guiadeen D, Singer M, Argentieri D, Hlasta DJ, Wachter M. Grant EB, et al. Among authors: wachter m. Bioorg Med Chem Lett. 2001 Nov 5;11(21):2817-20. doi: 10.1016/s0960-894x(01)00522-4. Bioorg Med Chem Lett. 2001. PMID: 11597407

10

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.

Wadsworth SA, Cavender DE, Beers SA, Lalan P, Schafer PH, Malloy EA, Wu W, Fahmy B, Olini GC, Davis JE, Pellegrino-Gensey JL, Wachter MP, Siekierka JJ. Wadsworth SA, et al. Among authors: wachter mp. J Pharmacol Exp Ther. 1999 Nov;291(2):680-7. J Pharmacol Exp Ther. 1999. PMID: 10525088

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