Skarzynski T - Search Results

1

The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin.

Tsai FT, Singh OM, Skarzynski T, Wonacott AJ, Weston S, Tucker A, Pauptit RA, Breeze AL, Poyser JP, O'Brien R, Ladbury JE, Wigley DB. Tsai FT, et al. Among authors: skarzynski t. Proteins. 1997 May;28(1):41-52. Proteins. 1997. PMID: 9144789

2

Crystallization of inhibitor complexes of an N-terminal 24 kDa fragment of the DNA gyrase B protein.

Lewis RJ, Singh OM, Smith CV, Maxwell A, Skarzynski T, Wonacott AJ, Wigley DB. Lewis RJ, et al. Among authors: skarzynski t. J Mol Biol. 1994 Aug 5;241(1):128-30. doi: 10.1006/jmbi.1994.1480. J Mol Biol. 1994. PMID: 8051702

3

The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography.

Lewis RJ, Singh OM, Smith CV, Skarzynski T, Maxwell A, Wonacott AJ, Wigley DB. Lewis RJ, et al. Among authors: skarzynski t. EMBO J. 1996 Mar 15;15(6):1412-20. EMBO J. 1996. PMID: 8635474 Free PMC article.

4

Coenzyme-induced conformational changes in glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus.

Skarzyński T, Wonacott AJ. Skarzyński T, et al. J Mol Biol. 1988 Oct 20;203(4):1097-118. doi: 10.1016/0022-2836(88)90130-1. J Mol Biol. 1988. PMID: 3210237

5

Structure of holo-glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus at 1.8 A resolution.

Skarzyński T, Moody PC, Wonacott AJ. Skarzyński T, et al. J Mol Biol. 1987 Jan 5;193(1):171-87. doi: 10.1016/0022-2836(87)90635-8. J Mol Biol. 1987. PMID: 3586018

6

Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin.

Skarzynski T, Mistry A, Wonacott A, Hutchinson SE, Kelly VA, Duncan K. Skarzynski T, et al. Structure. 1996 Dec 15;4(12):1465-74. doi: 10.1016/s0969-2126(96)00153-0. Structure. 1996. PMID: 8994972 Free article.

7

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.

Taylor NR, Cleasby A, Singh O, Skarzynski T, Wonacott AJ, Smith PW, Sollis SL, Howes PD, Cherry PC, Bethell R, Colman P, Varghese J. Taylor NR, et al. Among authors: skarzynski t. J Med Chem. 1998 Mar 12;41(6):798-807. doi: 10.1021/jm9703754. J Med Chem. 1998. PMID: 9526556

8

Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA.

Jovine L, Hainzl T, Oubridge C, Scott WG, Li J, Sixma TK, Wonacott A, Skarzynski T, Nagai K. Jovine L, et al. Among authors: skarzynski t. Structure. 2000 May 15;8(5):527-40. doi: 10.1016/s0969-2126(00)00137-4. Structure. 2000. PMID: 10801497 Free article.

9

Crystal structures of ASK1-inhibtor complexes provide a platform for structure-based drug design.

Singh O, Shillings A, Craggs P, Wall I, Rowland P, Skarzynski T, Hobbs CI, Hardwick P, Tanner R, Blunt M, Witty DR, Smith KJ. Singh O, et al. Among authors: skarzynski t. Protein Sci. 2013 Aug;22(8):1071-7. doi: 10.1002/pro.2298. Epub 2013 Jul 3. Protein Sci. 2013. PMID: 23776076 Free PMC article.

10

The x-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution.

Cleasby A, Wonacott A, Skarzynski T, Hubbard RE, Davies GJ, Proudfoot AE, Bernard AR, Payton MA, Wells TN. Cleasby A, et al. Among authors: skarzynski t. Nat Struct Biol. 1996 May;3(5):470-9. doi: 10.1038/nsb0596-470. Nat Struct Biol. 1996. PMID: 8612079

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