Ladbury JE - Search Results

1

The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin.

Tsai FT, Singh OM, Skarzynski T, Wonacott AJ, Weston S, Tucker A, Pauptit RA, Breeze AL, Poyser JP, O'Brien R, Ladbury JE, Wigley DB. Tsai FT, et al. Among authors: ladbury je. Proteins. 1997 May;28(1):41-52. Proteins. 1997. PMID: 9144789

2

The adaptability of Escherichia coli thioredoxin to non-conservative amino acid substitutions.

O'Brien R, Wynn R, Driscoll PC, Davis B, Plaxco KW, Sturtevant JM, Ladbury JE. O'Brien R, et al. Among authors: ladbury je. Protein Sci. 1997 Jun;6(6):1325-32. doi: 10.1002/pro.5560060621. Protein Sci. 1997. PMID: 9194193 Free PMC article.

3

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone.

Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Prodromou C, et al. Among authors: ladbury je. Cell. 1997 Jul 11;90(1):65-75. doi: 10.1016/s0092-8674(00)80314-1. Cell. 1997. PMID: 9230303 Free article.

4

Structural basis for recognition of dipeptides by peptide transporters.

Payne JW, Grail BM, Gupta S, Ladbury JE, Marshall NJ, O'Brien R, Payne GM. Payne JW, et al. Among authors: ladbury je. Arch Biochem Biophys. 2000 Dec 1;384(1):9-23. doi: 10.1006/abbi.2000.2084. Arch Biochem Biophys. 2000. PMID: 11147841

5

Localization and characterization of the hyaluronan-binding site on the link module from human TSG-6.

Kahmann JD, O'Brien R, Werner JM, Heinegârd D, Ladbury JE, Campbell ID, Day AJ. Kahmann JD, et al. Among authors: ladbury je. Structure. 2000 Jul 15;8(7):763-74. doi: 10.1016/s0969-2126(00)00163-5. Structure. 2000. PMID: 10903951 Free article.

6

Identification of novel fragment compounds targeted against the pY pocket of v-Src SH2 by computational and NMR screening and thermodynamic evaluation.

Taylor JD, Gilbert PJ, Williams MA, Pitt WR, Ladbury JE. Taylor JD, et al. Among authors: ladbury je. Proteins. 2007 Jun 1;67(4):981-90. doi: 10.1002/prot.21369. Proteins. 2007. PMID: 17393456

7

Reversal of halophilicity in a protein-DNA interaction by limited mutation strategy.

Bergqvist S, Williams MA, O'Brien R, Ladbury JE. Bergqvist S, et al. Among authors: ladbury je. Structure. 2002 May;10(5):629-37. doi: 10.1016/s0969-2126(02)00749-9. Structure. 2002. PMID: 12015146 Free article.

8

Alternative modes of binding of proteins with tandem SH2 domains.

O'Brien R, Rugman P, Renzoni D, Layton M, Handa R, Hilyard K, Waterfield MD, Driscoll PC, Ladbury JE. O'Brien R, et al. Among authors: ladbury je. Protein Sci. 2000 Mar;9(3):570-9. doi: 10.1110/ps.9.3.570. Protein Sci. 2000. PMID: 10752619 Free PMC article.

9

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin.

Roe SM, Prodromou C, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Roe SM, et al. Among authors: ladbury je. J Med Chem. 1999 Jan 28;42(2):260-6. doi: 10.1021/jm980403y. J Med Chem. 1999. PMID: 9925731

10

Site-specific cation binding mediates TATA binding protein-DNA interaction from a hyperthermophilic archaeon.

Bergqvist S, O'Brien R, Ladbury JE. Bergqvist S, et al. Among authors: ladbury je. Biochemistry. 2001 Feb 27;40(8):2419-25. doi: 10.1021/bi002488m. Biochemistry. 2001. PMID: 11327862

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