Garrett MD - Search Results

1

New functional activities for the p21 family of CDK inhibitors.

LaBaer J, Garrett MD, Stevenson LF, Slingerland JM, Sandhu C, Chou HS, Fattaey A, Harlow E. LaBaer J, et al. Among authors: garrett md. Genes Dev. 1997 Apr 1;11(7):847-62. doi: 10.1101/gad.11.7.847. Genes Dev. 1997. PMID: 9106657 Free article.

2

CDK inhibition and cancer therapy.

Garrett MD, Fattaey A. Garrett MD, et al. Curr Opin Genet Dev. 1999 Feb;9(1):104-11. doi: 10.1016/s0959-437x(99)80015-x. Curr Opin Genet Dev. 1999. PMID: 10072351 Review.

3

Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6.

Fry DW, Bedford DC, Harvey PH, Fritsch A, Keller PR, Wu Z, Dobrusin E, Leopold WR, Fattaey A, Garrett MD. Fry DW, et al. Among authors: garrett md. J Biol Chem. 2001 May 18;276(20):16617-23. doi: 10.1074/jbc.M008867200. Epub 2001 Feb 6. J Biol Chem. 2001. PMID: 11278443 Free article.

4

Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases.

Barvian M, Boschelli DH, Cossrow J, Dobrusin E, Fattaey A, Fritsch A, Fry D, Harvey P, Keller P, Garrett M, La F, Leopold W, McNamara D, Quin M, Trumpp-Kallmeyer S, Toogood P, Wu Z, Zhang E. Barvian M, et al. J Med Chem. 2000 Nov 30;43(24):4606-16. doi: 10.1021/jm000271k. J Med Chem. 2000. PMID: 11101352

5

Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors.

Collins I, Garrett MD. Collins I, et al. Among authors: garrett md. Curr Opin Pharmacol. 2005 Aug;5(4):366-73. doi: 10.1016/j.coph.2005.04.009. Curr Opin Pharmacol. 2005. PMID: 15964238 Review.

6

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription.

Ma T, Van Tine BA, Wei Y, Garrett MD, Nelson D, Adams PD, Wang J, Qin J, Chow LT, Harper JW. Ma T, et al. Among authors: garrett md. Genes Dev. 2000 Sep 15;14(18):2298-313. doi: 10.1101/gad.829500. Genes Dev. 2000. PMID: 10995387 Free PMC article.

7

Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases.

Martin NG, McAndrew PC, Eve PD, Garrett MD. Martin NG, et al. Among authors: garrett md. FEBS J. 2008 Jun;275(12):3099-109. doi: 10.1111/j.1742-4658.2008.06463.x. Epub 2008 May 8. FEBS J. 2008. PMID: 18479465 Free article.

8

Clinical anticancer drug development: targeting the cyclin-dependent kinases.

Benson C, Kaye S, Workman P, Garrett M, Walton M, de Bono J. Benson C, et al. Br J Cancer. 2005 Jan 17;92(1):7-12. doi: 10.1038/sj.bjc.6602229. Br J Cancer. 2005. PMID: 15558073 Free PMC article. Review.

9

The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway.

Whittaker SR, Walton MI, Garrett MD, Workman P. Whittaker SR, et al. Among authors: garrett md. Cancer Res. 2004 Jan 1;64(1):262-72. doi: 10.1158/0008-5472.can-03-0110. Cancer Res. 2004. PMID: 14729633

10

In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.

Raynaud FI, Whittaker SR, Fischer PM, McClue S, Walton MI, Barrie SE, Garrett MD, Rogers P, Clarke SJ, Kelland LR, Valenti M, Brunton L, Eccles S, Lane DP, Workman P. Raynaud FI, et al. Among authors: garrett md. Clin Cancer Res. 2005 Jul 1;11(13):4875-87. doi: 10.1158/1078-0432.CCR-04-2264. Clin Cancer Res. 2005. PMID: 16000586

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