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Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation.
Del Papa N, Guidali L, Sala A, Buccellati C, Khamashta MA, Ichikawa K, Koike T, Balestrieri G, Tincani A, Hughes GR, Meroni PL. Del Papa N, et al. Among authors: koike t. Arthritis Rheum. 1997 Mar;40(3):551-61. doi: 10.1002/art.1780400322. Arthritis Rheum. 1997. PMID: 9082944
Human beta 2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-beta 2-glycoprotein I antibodies.
Del Papa N, Sheng YH, Raschi E, Kandiah DA, Tincani A, Khamashta MA, Atsumi T, Hughes GR, Ichikawa K, Koike T, Balestrieri G, Krilis SA, Meroni PL. Del Papa N, et al. Among authors: koike t. J Immunol. 1998 Jun 1;160(11):5572-8. J Immunol. 1998. PMID: 9605162 Free article.
A chimeric antibody with the human gamma1 constant region as a putative standard for assays to detect IgG beta2-glycoprotein I-dependent anticardiolipin and anti-beta2-glycoprotein I antibodies.
Ichikawa K, Tsutsumi A, Atsumi T, Matsuura E, Kobayashi S, Hughes GR, Khamashta MA, Koike T. Ichikawa K, et al. Among authors: koike t. Arthritis Rheum. 1999 Nov;42(11):2461-70. doi: 10.1002/1529-0131(199911)42:11<2461::AID-ANR25>3.0.CO;2-O. Arthritis Rheum. 1999. PMID: 10555042 Free article.
Binding of anticardiolipin antibodies to protein C via beta2-glycoprotein I (beta2-GPI): a possible mechanism in the inhibitory effect of antiphospholipid antibodies on the protein C system.
Atsumi T, Khamashta MA, Amengual O, Donohoe S, Mackie I, Ichikawa K, Koike T, Hughes GR. Atsumi T, et al. Among authors: koike t. Clin Exp Immunol. 1998 May;112(2):325-33. doi: 10.1046/j.1365-2249.1998.00582.x. Clin Exp Immunol. 1998. PMID: 9649198 Free PMC article.
2,641 results