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Mutations in the insulin receptor gene.
Taylor SI, Cama A, Accili D, Barbetti F, Quon MJ, de la Luz Sierra M, Suzuki Y, Koller E, Levy-Toledano R, Wertheimer E, et al. Taylor SI, et al. Among authors: accili d. Endocr Rev. 1992 Aug;13(3):566-95. doi: 10.1210/edrv-13-3-566. Endocr Rev. 1992. PMID: 1330507 Review. No abstract available.
A mutation in the extracellular domain of the insulin receptor impairs the ability of insulin to stimulate receptor autophosphorylation.
Accili D, Mosthaf L, Ullrich A, Taylor SI. Accili D, et al. J Biol Chem. 1991 Jan 5;266(1):434-9. J Biol Chem. 1991. PMID: 1845971 Free article.
We have previously reported that a mutation substituting valine for Phe382 in the alpha-subunit of the insulin receptor is associated with impaired transport of the mutant receptor to the plasma membrane (Accili, D., Frapier, C., Mosthaf, L., McKeon, C., Elbein, S. …
We have previously reported that a mutation substituting valine for Phe382 in the alpha-subunit of the insulin receptor is associated with i …
335 results