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Page 1
Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study.
Tamamura H, Omagari A, Hiramatsu K, Oishi S, Habashita H, Kanamoto T, Gotoh K, Yamamoto N, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: habashita h. Bioorg Med Chem. 2002 May;10(5):1417-26. doi: 10.1016/s0968-0896(01)00419-9. Bioorg Med Chem. 2002. PMID: 11886804
Palladium(0)-Catalyzed Isomerization Reactions of Aziridines Bearing an alpha,beta-Unsaturated Ester Group: A Thermodynamic Preference for Chiral Alkyl (2E)-4,5-cis-4,5-Epimino-N-(alkyl- or arylsulfonyl) 2-Enoates over the Other Three Stereoisomers.
Ibuka T, Mimura N, Ohno H, Nakai K, Akaji M, Habashita H, Tamamura H, Miwa Y, Taga T, Fujii N, Yamamoto Y. Ibuka T, et al. Among authors: habashita h. J Org Chem. 1997 May 2;62(9):2982-2991. doi: 10.1021/jo962094u. J Org Chem. 1997. PMID: 11671663
Discovery of a new chemical lead for a matrix metalloproteinase inhibitor.
Ikura M, Nakatani S, Yamamoto S, Habashita H, Sugiura T, Takahashi K, Ogawa K, Ohno H, Nakai H, Toda M. Ikura M, et al. Among authors: habashita h. Bioorg Med Chem. 2006 Jun 15;14(12):4241-52. doi: 10.1016/j.bmc.2006.01.059. Epub 2006 Feb 14. Bioorg Med Chem. 2006. PMID: 16481176
Discovery of orally available spirodiketopiperazine-based CCR5 antagonists.
Nishizawa R, Nishiyama T, Hisaichi K, Hirai K, Habashita H, Takaoka Y, Tada H, Sagawa K, Shibayama S, Maeda K, Mitsuya H, Nakai H, Fukushima D, Toda M. Nishizawa R, et al. Among authors: habashita h. Bioorg Med Chem. 2010 Jul 15;18(14):5208-23. doi: 10.1016/j.bmc.2010.05.057. Epub 2010 May 25. Bioorg Med Chem. 2010. PMID: 20542438 Free PMC article.
Structure-activity relationship studies of S1P agonists with a dihydronaphthalene scaffold.
Kurata H, Kusumi K, Otsuki K, Suzuki R, Kurono M, Tokuda N, Takada Y, Shioya H, Mizuno H, Komiya T, Ono T, Hagiya H, Minami M, Nakade S, Habashita H. Kurata H, et al. Among authors: habashita h. Bioorg Med Chem Lett. 2012 Jan 1;22(1):144-8. doi: 10.1016/j.bmcl.2011.11.048. Epub 2011 Nov 20. Bioorg Med Chem Lett. 2012. PMID: 22153936
Design and synthesis of novel metalloproteinase inhibitors.
Nakatani S, Ikura M, Yamamoto S, Nishita Y, Itadani S, Habashita H, Sugiura T, Ogawa K, Ohno H, Takahashi K, Nakai H, Toda M. Nakatani S, et al. Among authors: habashita h. Bioorg Med Chem. 2006 Aug 1;14(15):5402-22. doi: 10.1016/j.bmc.2006.03.032. Epub 2006 Apr 18. Bioorg Med Chem. 2006. PMID: 16621578
25 results