Schaper KJ - Search Results

1

Structure-activity relationship studies on benzofuran analogs of propafenone-type modulators of tumor cell multidrug resistance.

Ecker G, Chiba P, Hitzler M, Schmid D, Visser K, Cordes HP, Csöllei J, Seydel JK, Schaper KJ. Ecker G, et al. Among authors: schaper kj. J Med Chem. 1996 Nov 22;39(24):4767-74. doi: 10.1021/jm960384x. J Med Chem. 1996. PMID: 8941391

2

Synthesis and quantitative structure-activity relationships of anticonvulsant 2,3,6-triaminopyridines.

Seydel JK, Schaper KJ, Coats EA, Cordes HP, Emig P, Engel J, Kutscher B, Polymeropoulos EE. Seydel JK, et al. Among authors: schaper kj. J Med Chem. 1994 Sep 16;37(19):3016-22. doi: 10.1021/jm00045a005. J Med Chem. 1994. PMID: 7932523

3

Estimation of the chemosensitizing activity of modulators of multi-drug resistance via combined simultaneous analysis of sigmoidal dose-response curves.

Ecker G, Chiba P, Schaper KJ. Ecker G, et al. Among authors: schaper kj. J Pharm Pharmacol. 1997 Mar;49(3):305-9. doi: 10.1111/j.2042-7158.1997.tb06801.x. J Pharm Pharmacol. 1997. PMID: 9231351

4

A combined Hansch/Free-Wilson approach as predictive tool in QSAR studies on propafenone-type modulators of multidrug resistance.

Tmej C, Chiba P, Huber M, Richter E, Hitzler M, Schaper KJ, Ecker G. Tmej C, et al. Among authors: schaper kj. Arch Pharm (Weinheim). 1998 Jul-Aug;331(7-8):233-40. doi: 10.1002/(sici)1521-4184(199807)331:7/8<233::aid-ardp233>3.0.co;2-2. Arch Pharm (Weinheim). 1998. PMID: 9747179

5

Mode of action and quantitative structure-activity correlations of tuberculostatic drugs of the isonicotinic acid hydrazide type.

Seydel JK, Schaper KJ, Wempe E, Cordes HP. Seydel JK, et al. Among authors: schaper kj. J Med Chem. 1976 Apr;19(4):483-92. doi: 10.1021/jm00226a007. J Med Chem. 1976. PMID: 817022

6

Artificial neural networks as versatile tools for prediction of MDR-modulatory activity.

Tmej C, Chiba P, Schaper KJ, Ecker G, Fleischhacker W. Tmej C, et al. Among authors: schaper kj. Adv Exp Med Biol. 1999;457:95-105. doi: 10.1007/978-1-4615-4811-9_12. Adv Exp Med Biol. 1999. PMID: 10500785

7

Sulfonamide structure-activity relationships in a cell-free system. 2. Proof for the formation of a sulfonamide-containing folate analog.

Bock L, Miller GH, Schaper KJ, Seydel JK. Bock L, et al. Among authors: schaper kj. J Med Chem. 1974 Jan;17(1):23-8. doi: 10.1021/jm00247a006. J Med Chem. 1974. PMID: 4357096 No abstract available.

8

Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.

Otzen T, Wempe EG, Kunz B, Bartels R, Lehwark-Yvetot G, Hänsel W, Schaper KJ, Seydel JK. Otzen T, et al. Among authors: schaper kj. J Med Chem. 2004 Jan 1;47(1):240-53. doi: 10.1021/jm030931w. J Med Chem. 2004. PMID: 14695838

9

Structure-activity correlations in a homologous series of 2-substituted isonicotinic acid hydrazides.

Schaper KJ, Seydel JK. Schaper KJ, et al. Experientia Suppl. 1976;23:119-24. doi: 10.1007/978-3-0348-5795-6_16. Experientia Suppl. 1976. PMID: 821772 No abstract available.

10

Quantitative structure-pharmacokinetic relationships and drug design.

Seydel JK, Schaper KJ. Seydel JK, et al. Among authors: schaper kj. Pharmacol Ther. 1981;15(2):131-82. doi: 10.1016/0163-7258(81)90040-1. Pharmacol Ther. 1981. PMID: 6124012 Review. No abstract available.

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