Chiba P - Search Results

1

Structure-activity relationship studies on benzofuran analogs of propafenone-type modulators of tumor cell multidrug resistance.

Ecker G, Chiba P, Hitzler M, Schmid D, Visser K, Cordes HP, Csöllei J, Seydel JK, Schaper KJ. Ecker G, et al. Among authors: chiba p. J Med Chem. 1996 Nov 22;39(24):4767-74. doi: 10.1021/jm960384x. J Med Chem. 1996. PMID: 8941391

2

Synthesis and multidrug-resistance modulating activity of a series of thienothiazines.

Chiba P, Erker T, Galanski M, Hitzler M, Ecker GF. Chiba P, et al. Arch Pharm (Weinheim). 2002 May;335(5):223-8. doi: 10.1002/1521-4184(200205)335:5<223::AID-ARDP223>3.0.CO;2-D. Arch Pharm (Weinheim). 2002. PMID: 12210779

3

Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.

Jabeen I, Pleban K, Rinner U, Chiba P, Ecker GF. Jabeen I, et al. Among authors: chiba p. J Med Chem. 2012 Apr 12;55(7):3261-73. doi: 10.1021/jm201705f. Epub 2012 Mar 27. J Med Chem. 2012. PMID: 22452412 Free PMC article.

4

Structure-activity relationship studies of propafenone analogs based on P-glycoprotein ATPase activity measurements.

Schmid D, Ecker G, Kopp S, Hitzler M, Chiba P. Schmid D, et al. Among authors: chiba p. Biochem Pharmacol. 1999 Nov 1;58(9):1447-56. doi: 10.1016/s0006-2952(99)00229-4. Biochem Pharmacol. 1999. PMID: 10513988

5

Interaction field based and hologram based QSAR analysis of propafenone-type modulators of multidrug resistance.

Kaiser D, Smiesko M, Kopp S, Chiba P, Ecker GF. Kaiser D, et al. Among authors: chiba p. Med Chem. 2005 Sep;1(5):431-44. doi: 10.2174/1573406054864061. Med Chem. 2005. PMID: 16787327

6

Studies on propafenone-type modulators of multidrug-resistance IV1): synthesis and pharmacological activity of 5-hydroxy and 5-benzyloxy derivatives.

Chiba P, Tell B, Jäger W, Richter E, Hitzler M, Ecker G. Chiba P, et al. Arch Pharm (Weinheim). 1997 Nov;330(11):343-7. doi: 10.1002/ardp.19973301105. Arch Pharm (Weinheim). 1997. PMID: 9431026

7

A combined Hansch/Free-Wilson approach as predictive tool in QSAR studies on propafenone-type modulators of multidrug resistance.

Tmej C, Chiba P, Huber M, Richter E, Hitzler M, Schaper KJ, Ecker G. Tmej C, et al. Among authors: chiba p. Arch Pharm (Weinheim). 1998 Jul-Aug;331(7-8):233-40. doi: 10.1002/(sici)1521-4184(199807)331:7/8<233::aid-ardp233>3.0.co;2-2. Arch Pharm (Weinheim). 1998. PMID: 9747179

8

Substituted 4-acylpyrazoles and 4-acylpyrazolones: synthesis and multidrug resistance-modulating activity.

Chiba P, Holzer W, Landau M, Bechmann G, Lorenz K, Plagens B, Hitzler M, Richter E, Ecker G. Chiba P, et al. J Med Chem. 1998 Oct 8;41(21):4001-11. doi: 10.1021/jm980121y. J Med Chem. 1998. PMID: 9767638

9

Synthesis and pharmacological activity of the stereoisomers of GP-88, a propafenone-type modulator of multidrug resistance.

Chiba P, Rebitzer S, Richter E, Hitzler M, Ecker G. Chiba P, et al. Bioorg Med Chem Lett. 1998 Apr 7;8(7):829-32. doi: 10.1016/s0960-894x(98)00115-2. Bioorg Med Chem Lett. 1998. PMID: 9871549

10

Synthesis and in vitro multidrug resistance modulating activity of a series of dihydrobenzopyrans and tetrahydroquinolines.

Hiessböck R, Wolf C, Richter E, Hitzler M, Chiba P, Kratzel M, Ecker G. Hiessböck R, et al. Among authors: chiba p. J Med Chem. 1999 Jun 3;42(11):1921-6. doi: 10.1021/jm980517+. J Med Chem. 1999. PMID: 10354400

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