Dilworth FJ - Search Results

1

Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase.

White JA, Guo YD, Baetz K, Beckett-Jones B, Bonasoro J, Hsu KE, Dilworth FJ, Jones G, Petkovich M. White JA, et al. Among authors: dilworth fj. J Biol Chem. 1996 Nov 22;271(47):29922-7. doi: 10.1074/jbc.271.47.29922. J Biol Chem. 1996. PMID: 8939936 Free article.

2

Different mechanisms of hydroxylation site selection by liver and kidney cytochrome P450 species (CYP27 and CYP24) involved in vitamin D metabolism.

Dilworth FJ, Scott I, Green A, Strugnell S, Guo YD, Roberts EA, Kremer R, Calverley MJ, Makin HL, Jones G. Dilworth FJ, et al. J Biol Chem. 1995 Jul 14;270(28):16766-74. doi: 10.1074/jbc.270.28.16766. J Biol Chem. 1995. PMID: 7622489 Free article.

3

Construction of a P450c27 fusion enzyme: a useful tool for analysis of vitamin D3 25-hydroxylase activity.

Dilworth FJ, Black SM, Guo YD, Miller WL, Jones G. Dilworth FJ, et al. Biochem J. 1996 Nov 15;320 ( Pt 1)(Pt 1):267-71. doi: 10.1042/bj3200267. Biochem J. 1996. PMID: 8947497 Free PMC article.

4

cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450.

White JA, Beckett-Jones B, Guo YD, Dilworth FJ, Bonasoro J, Jones G, Petkovich M. White JA, et al. Among authors: dilworth fj. J Biol Chem. 1997 Jul 25;272(30):18538-41. doi: 10.1074/jbc.272.30.18538. J Biol Chem. 1997. PMID: 9228017 Free article.

5

Metabolism of the vitamin D analog EB1089 by cultured human cells: redirection of hydroxylation site to distal carbons of the side-chain.

Shankar VN, Dilworth FJ, Makin HL, Schroeder NJ, Trafford DJ, Kissmeyer AM, Calverley MJ, Binderup E, Jones G. Shankar VN, et al. Among authors: dilworth fj. Biochem Pharmacol. 1997 Mar 21;53(6):783-93. doi: 10.1016/s0006-2952(96)00815-5. Biochem Pharmacol. 1997. PMID: 9113099

6

Increased biological activity of 20-epi-1,25-dihydroxyvitamin D3 is due to reduced catabolism and altered protein binding.

Dilworth FJ, Calverley MJ, Makin HL, Jones G. Dilworth FJ, et al. Biochem Pharmacol. 1994 Mar 15;47(6):987-93. doi: 10.1016/0006-2952(94)90409-x. Biochem Pharmacol. 1994. PMID: 8147918

7

The vitamin D analog, KH1060, is rapidly degraded both in vivo and in vitro via several pathways: principal metabolites generated retain significant biological activity.

Dilworth FJ, Williams GR, Kissmeyer AM, Nielsen JL, Binderup E, Calverley MJ, Makin HL, Jones G. Dilworth FJ, et al. Endocrinology. 1997 Dec;138(12):5485-96. doi: 10.1210/endo.138.12.5594. Endocrinology. 1997. PMID: 9389535

8

Contribution of several metabolites of the vitamin D analog 20-epi-22-oxa-24a,26a,27a-tri-homo-1,25-(OH)(2) vitamin D(3) (KH 1060) to the overall biological activity of KH1060 by a shared mechanism of action.

van den Bemd GC, Dilworth FJ, Makin HL, Prahl JM, Deluca HF, Jones G, Pols HA, van Leeuwen JP. van den Bemd GC, et al. Among authors: dilworth fj. Biochem Pharmacol. 2000 Mar 15;59(6):621-7. doi: 10.1016/s0006-2952(99)00371-8. Biochem Pharmacol. 2000. PMID: 10677578

9

Teashirt-3, a novel regulator of muscle differentiation, associates with BRG1-associated factor 57 (BAF57) to inhibit myogenin gene expression.

Faralli H, Martin E, Coré N, Liu QC, Filippi P, Dilworth FJ, Caubit X, Fasano L. Faralli H, et al. Among authors: dilworth fj. J Biol Chem. 2011 Jul 1;286(26):23498-510. doi: 10.1074/jbc.M110.206003. Epub 2011 May 4. J Biol Chem. 2011. PMID: 21543328 Free PMC article.

10

Ligand-dependent activation of transcription in vitro by retinoic acid receptor alpha/retinoid X receptor alpha heterodimers that mimics transactivation by retinoids in vivo.

Dilworth FJ, Fromental-Ramain C, Remboutsika E, Benecke A, Chambon P. Dilworth FJ, et al. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1995-2000. doi: 10.1073/pnas.96.5.1995. Proc Natl Acad Sci U S A. 1999. PMID: 10051583 Free PMC article.

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