Esler WP - Search Results

1

Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence.

Esler WP, Stimson ER, Ghilardi JR, Lu YA, Felix AM, Vinters HV, Mantyh PW, Lee JP, Maggio JE. Esler WP, et al. Biochemistry. 1996 Nov 5;35(44):13914-21. doi: 10.1021/bi961302+. Biochemistry. 1996. PMID: 8909288

2

In vitro growth of Alzheimer's disease beta-amyloid plaques displays first-order kinetics.

Esler WP, Stimson ER, Ghilardi JR, Vinters HV, Lee JP, Mantyh PW, Maggio JE. Esler WP, et al. Biochemistry. 1996 Jan 23;35(3):749-57. doi: 10.1021/bi951685w. Biochemistry. 1996. PMID: 8547255

3

Zinc-induced aggregation of human and rat beta-amyloid peptides in vitro.

Esler WP, Stimson ER, Jennings JM, Ghilardi JR, Mantyh PW, Maggio JE. Esler WP, et al. J Neurochem. 1996 Feb;66(2):723-32. doi: 10.1046/j.1471-4159.1996.66020723.x. J Neurochem. 1996. PMID: 8592145

4

A beta deposition inhibitor screen using synthetic amyloid.

Esler WP, Stimson ER, Ghilardi JR, Felix AM, Lu YA, Vinters HV, Mantyh PW, Maggio JE. Esler WP, et al. Nat Biotechnol. 1997 Mar;15(3):258-63. doi: 10.1038/nbt0397-258. Nat Biotechnol. 1997. PMID: 9062926

5

Stereochemical specificity of Alzheimer's disease beta-peptide assembly.

Esler WP, Stimson ER, Fishman JB, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE. Esler WP, et al. Biopolymers. 1999 May;49(6):505-14. doi: 10.1002/(SICI)1097-0282(199905)49:6<505::AID-BIP8>3.0.CO;2-I. Biopolymers. 1999. PMID: 10193196

6

Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations.

Tseng BP, Esler WP, Clish CB, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Lee JP, Maggio JE. Tseng BP, et al. Among authors: esler wp. Biochemistry. 1999 Aug 10;38(32):10424-31. doi: 10.1021/bi990718v. Biochemistry. 1999. PMID: 10441137

7

Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism.

Esler WP, Stimson ER, Jennings JM, Vinters HV, Ghilardi JR, Lee JP, Mantyh PW, Maggio JE. Esler WP, et al. Biochemistry. 2000 May 30;39(21):6288-95. doi: 10.1021/bi992933h. Biochemistry. 2000. PMID: 10828941

8

Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid.

Esler WP, Felix AM, Stimson ER, Lachenmann MJ, Ghilardi JR, Lu YA, Vinters HV, Mantyh PW, Lee JP, Maggio JE. Esler WP, et al. J Struct Biol. 2000 Jun;130(2-3):174-83. doi: 10.1006/jsbi.2000.4276. J Struct Biol. 2000. PMID: 10940224

9

Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease.

Esler WP, Marshall JR, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE. Esler WP, et al. Amyloid. 2002 Mar;9(1):1-12. doi: 10.3109/13506120209072439. Amyloid. 2002. PMID: 12000192

10

Deposition of soluble amyloid-beta onto amyloid templates: with application for the identification of amyloid fibril extension inhibitors.

Esler WP, Stimson ER, Mantyh PW, Maggio JE. Esler WP, et al. Methods Enzymol. 1999;309:350-74. doi: 10.1016/s0076-6879(99)09025-4. Methods Enzymol. 1999. PMID: 10507035 No abstract available.

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