Thomas RS - Search Results

1

Physiologically based pharmacokinetic/pharmacodynamic modeling of the toxicologic interaction between carbon tetrachloride and Kepone.

el-Masri HA, Thomas RS, Sabados GR, Phillips JK, Constan AA, Benjamin SA, Andersen ME, Mehendale HM, Yang RS. el-Masri HA, et al. Among authors: thomas rs. Arch Toxicol. 1996;70(11):704-13. doi: 10.1007/s002040050331. Arch Toxicol. 1996. PMID: 8896716

2

The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures.

Yang RS, el-Masri HA, Thomas RS, Constan AA, Tessari JD. Yang RS, et al. Among authors: thomas rs. Toxicol Lett. 1995 Sep;79(1-3):193-200. doi: 10.1016/0378-4274(95)03370-z. Toxicol Lett. 1995. PMID: 7570656 Review.

3

Physiologically based pharmacokinetic/pharmacodynamic modeling of chemical mixtures and possible applications in risk assessment.

el-Masri HA, Thomas RS, Benjamin SA, Yang RS. el-Masri HA, et al. Among authors: thomas rs. Toxicology. 1995 Dec 28;105(2-3):275-82. doi: 10.1016/0300-483x(95)03222-2. Toxicology. 1995. PMID: 8571364

4

The use of physiologically-based pharmacokinetic/pharmacodynamic dosimetry models for chemical mixtures.

Yang RS, el-Masri HA, Thomas RS, Constan AA. Yang RS, et al. Among authors: thomas rs. Toxicol Lett. 1995 Dec;82-83:497-504. doi: 10.1016/0378-4274(95)03579-6. Toxicol Lett. 1995. PMID: 8597101 Review.

5

Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL): a computational method.

Thomas RS, Lytle WE, Keefe TJ, Constan AA, Yang RS. Thomas RS, et al. Fundam Appl Toxicol. 1996 May;31(1):19-28. doi: 10.1006/faat.1996.0072. Fundam Appl Toxicol. 1996. PMID: 8998950

6

A physiologically based pharmacodynamic analysis of hepatic foci within a medium-term liver bioassay using pentachlorobenzene as a promoter and diethylnitrosamine as an initiator.

Thomas RS, Conolly RB, Gustafson DL, Long ME, Benjamin SA, Yang RS. Thomas RS, et al. Toxicol Appl Pharmacol. 2000 Jul 15;166(2):128-37. doi: 10.1006/taap.2000.8959. Toxicol Appl Pharmacol. 2000. PMID: 10896854

7

Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation.

Thomas RS, Bigelow PL, Keefe TJ, Yang RS. Thomas RS, et al. Am Ind Hyg Assoc J. 1996 Jan;57(1):23-32. doi: 10.1080/15428119691015188. Am Ind Hyg Assoc J. 1996. PMID: 8588550

8

PBPK modeling/Monte Carlo simulation of methylene chloride kinetic changes in mice in relation to age and acute, subchronic, and chronic inhalation exposure.

Thomas RS, Yang RS, Morgan DG, Moorman MP, Kermani HR, Sloane RA, O'Connor RW, Adkins B Jr, Gargas ML, Andersen ME. Thomas RS, et al. Environ Health Perspect. 1996 Aug;104(8):858-65. doi: 10.1289/ehp.96104858. Environ Health Perspect. 1996. PMID: 8875160 Free PMC article.

9

Enhanced regional expression of glutathione S-transferase P1-1 with colocalized AP-1 and CYP 1A2 induction in chlorobenzene-induced porphyria.

Thomas RS, Gustafson DL, Ramsdell HS, el-Masri HA, Benjamin SA, Yang RS. Thomas RS, et al. Toxicol Appl Pharmacol. 1998 May;150(1):22-31. doi: 10.1006/taap.1998.8385. Toxicol Appl Pharmacol. 1998. PMID: 9630449

10

Approaches to developing alternative and predictive toxicology based on PBPK/PD and QSAR modeling.

Yang RS, Thomas RS, Gustafson DL, Campain J, Benjamin SA, Verhaar HJ, Mumtaz MM. Yang RS, et al. Among authors: thomas rs. Environ Health Perspect. 1998 Dec;106 Suppl 6(Suppl 6):1385-93. doi: 10.1289/ehp.98106s61385. Environ Health Perspect. 1998. PMID: 9860897 Free PMC article. Review.

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