Boehm MF - Search Results

1

Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate.

Shirley MA, Bennani YL, Boehm MF, Breau AP, Pathirana C, Ulm EH. Shirley MA, et al. Among authors: boehm mf. Drug Metab Dispos. 1996 Mar;24(3):293-302. Drug Metab Dispos. 1996. PMID: 8820419

2

Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.

Boehm MF, McClurg MR, Pathirana C, Mangelsdorf D, White SK, Hebert J, Winn D, Goldman ME, Heyman RA. Boehm MF, et al. J Med Chem. 1994 Feb 4;37(3):408-14. doi: 10.1021/jm00029a013. J Med Chem. 1994. PMID: 8308867

3

Synthesis and Characterization of a Highly Potent and Selective Isotopically Labeled Retinoic Acid Receptor Ligand, ALRT1550.

Bennani YL, Marron KS, Mais DE, Flatten K, Nadzan AM, Boehm MF. Bennani YL, et al. Among authors: boehm mf. J Org Chem. 1998 Feb 6;63(3):543-550. doi: 10.1021/jo971409i. J Org Chem. 1998. PMID: 11672043

4

Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism.

Allegretto EA, McClurg MR, Lazarchik SB, Clemm DL, Kerner SA, Elgort MG, Boehm MF, White SK, Pike JW, Heyman RA. Allegretto EA, et al. Among authors: boehm mf. J Biol Chem. 1993 Dec 15;268(35):26625-33. J Biol Chem. 1993. PMID: 8253793 Free article.

5

Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.

Kasibhatla SR, Hong K, Biamonte MA, Busch DJ, Karjian PL, Sensintaffar JL, Kamal A, Lough RE, Brekken J, Lundgren K, Grecko R, Timony GA, Ran Y, Mansfield R, Fritz LC, Ulm E, Burrows FJ, Boehm MF. Kasibhatla SR, et al. Among authors: boehm mf. J Med Chem. 2007 Jun 14;50(12):2767-78. doi: 10.1021/jm050752+. Epub 2007 May 8. J Med Chem. 2007. PMID: 17488003

6

7'-substituted benzothiazolothio- and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors.

Zhang L, Fan J, Vu K, Hong K, Le Brazidec JY, Shi J, Biamonte M, Busch DJ, Lough RE, Grecko R, Ran Y, Sensintaffar JL, Kamal A, Lundgren K, Burrows FJ, Mansfield R, Timony GA, Ulm EH, Kasibhatla SR, Boehm MF. Zhang L, et al. Among authors: boehm mf. J Med Chem. 2006 Aug 24;49(17):5352-62. doi: 10.1021/jm051146h. J Med Chem. 2006. PMID: 16913725

7

Retinoid X receptor acts as a hormone receptor in vivo to induce a key metabolic enzyme for 1,25-dihydroxyvitamin D3.

Allegretto EA, Shevde N, Zou A, Howell SR, Boehm MF, Hollis BW, Pike JW. Allegretto EA, et al. Among authors: boehm mf. J Biol Chem. 1995 Oct 13;270(41):23906-9. doi: 10.1074/jbc.270.41.23906. J Biol Chem. 1995. PMID: 7592579 Free article.

8

9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation.

Bissonnette RP, Brunner T, Lazarchik SB, Yoo NJ, Boehm MF, Green DR, Heyman RA. Bissonnette RP, et al. Among authors: boehm mf. Mol Cell Biol. 1995 Oct;15(10):5576-85. doi: 10.1128/MCB.15.10.5576. Mol Cell Biol. 1995. PMID: 7565709 Free PMC article.

9

A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice.

Shalinsky DR, Bischoff ED, Lamph WW, Zhang L, Boehm MF, Davies PJ, Nadzan AM, Heyman RA. Shalinsky DR, et al. Among authors: boehm mf. Cancer Res. 1997 Jan 1;57(1):162-8. Cancer Res. 1997. PMID: 8988059

10

Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells.

Zhang L, Nadzan AM, Heyman RA, Love DL, Mais DE, Croston G, Lamph WW, Boehm MF. Zhang L, et al. Among authors: boehm mf. J Med Chem. 1996 Jul 5;39(14):2659-63. doi: 10.1021/jm960285j. J Med Chem. 1996. PMID: 8709094

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