Younkin S - Search Results

1

Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice.

Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G. Hsiao K, et al. Among authors: younkin s. Science. 1996 Oct 4;274(5284):99-102. doi: 10.1126/science.274.5284.99. Science. 1996. PMID: 8810256

2

Hsiao KK, Borchelt DR, Olson K, Johannsdottir R, Kitt C, Yunis W, Xu S, Eckman C, Younkin S, Price D, et al. Hsiao KK, et al. Among authors: younkin s. Neuron. 1995 Nov;15(5):1203-18. doi: 10.1016/0896-6273(95)90107-8. Neuron. 1995. PMID: 7576662 Free article.

3

Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein.

Zhang F, Eckman C, Younkin S, Hsiao KK, Iadecola C. Zhang F, et al. Among authors: younkin s. J Neurosci. 1997 Oct 15;17(20):7655-61. doi: 10.1523/JNEUROSCI.17-20-07655.1997. J Neurosci. 1997. PMID: 9315887 Free PMC article.

4

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein.

Iadecola C, Zhang F, Niwa K, Eckman C, Turner SK, Fischer E, Younkin S, Borchelt DR, Hsiao KK, Carlson GA. Iadecola C, et al. Among authors: younkin s. Nat Neurosci. 1999 Feb;2(2):157-61. doi: 10.1038/5715. Nat Neurosci. 1999. PMID: 10195200

5

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos L Jr, Eckman C, Golde TE, Younkin SG. Suzuki N, et al. Among authors: younkin sg. Science. 1994 May 27;264(5163):1336-40. doi: 10.1126/science.8191290. Science. 1994. PMID: 8191290

6

Accumulation of beta-amyloid fibrils in pancreas of transgenic mice.

Kawarabayashi T, Shoji M, Sato M, Sasaki A, Ho L, Eckman CB, Prada CM, Younkin SG, Kobayashi T, Tada N, Matsubara E, Iizuka T, Harigaya Y, Kasai K, Hirai S. Kawarabayashi T, et al. Among authors: younkin sg. Neurobiol Aging. 1996 Mar-Apr;17(2):215-22. doi: 10.1016/0197-4580(95)02061-6. Neurobiol Aging. 1996. PMID: 8744402

7

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

Chapman PF, White GL, Jones MW, Cooper-Blacketer D, Marshall VJ, Irizarry M, Younkin L, Good MA, Bliss TV, Hyman BT, Younkin SG, Hsiao KK. Chapman PF, et al. Among authors: younkin l, younkin sg. Nat Neurosci. 1999 Mar;2(3):271-6. doi: 10.1038/6374. Nat Neurosci. 1999. PMID: 10195221

8

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees.

Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG. Ertekin-Taner N, et al. Among authors: younkin lh, younkin sg. Science. 2000 Dec 22;290(5500):2303-4. doi: 10.1126/science.290.5500.2303. Science. 2000. PMID: 11125143

9

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.

Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Among authors: younkin s. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479

10

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.

Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K. Holcomb L, et al. Among authors: younkin s. Nat Med. 1998 Jan;4(1):97-100. doi: 10.1038/nm0198-097. Nat Med. 1998. PMID: 9427614

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